Sun, Jul 23, 2017 | updated 08:19 AM IST

Erectile dysfunction drugs don't cut prostate cancer risk

Updated: Aug 02, 2016 11:42 IST      
Erectile dysfunction drugs don't cut prostate cancer risk

Washington D.C, Aug 2 (ANI): Turns out, popping erectile dysfunction (ED) drugs cannot ward off your risk of prostate cancer.

ED is a common problem with a prevalence of 20 percent to 40 percent in the sixth decade of life and approaching 75 percent in the seventh decade. Drugs such as tadalafil, sildenafil and vardenafil are phosphodiesterase type 5 inhibitors (PDE-5is) commonly used to treat ED. Since PDE-5is were first introduced in 1998, their durability, safety, and efficacy for treating ED have been clearly demonstrated.

"In vitro mouse studies have suggested that these drugs might have some anticancer activity, but the evidence in human subjects is mixed," said lead investigator Stephen J. Freedland of the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai in Los Angeles, CA.

He added, "Given the routine use of PDE-5i and the possibility that these agents may have anticancer activity, we wanted to test the association between their use and risk of developing prostate cancer."

Using data from REDUCE, a four-year, multicenter study testing the effect of daily dutasteride to treat benign prostatic hyperplasia on prostate cancer risk in men, the authors analysed whether ED drug use by more than 6,500 patients may have affected overall prostate cancer risk and disease grade.

Of the 6,501 men in the study 364 used PDE-5i at baseline. During the study, prostate cancer was diagnosed in 71 of these men compared to 1,391 of 6,137 men who did not take PDE-5i, which was not significantly different. An analysis of prostate cancer grade also showed no correlation between PDE-5i use and low or high grade cancer. Because PDE-5i use was significantly higher among North American men, the authors looked for a regional effect. They found some correlation between ED use and lower prostate cancer diagnosis in North American men, but this did not reach statistical significance.

"Future studies with longer followup and larger study populations are warranted to determine the association between PDE-5i and prostate cancer," said first author Juzar Jamnagerwalla.

The study is published in The Journal of Urology. (ANI)

This is your brain on depression

Updated: Jul 22, 2017 13:55 IST     

Washington D.C. [USA], July 22 (ANI): Got the blues? According to a recent study, depression can change the structure of your brain.

Full Story >>

Rush-hour pollution may be more harmful than thought

Updated: Jul 22, 2017 10:57 IST     

Washington D.C. [USA], Jul 22 (ANI): Turns out, rush-hour commuters may be in for a double whammy of pollution exposure.

Full Story >>

TRAC, MedGenome announce Cancer Immunotherapy solution

Updated: Jul 22, 2017 06:24 IST     

New Delhi [India], July 22 (ANI): Toronto Recombinant Antibody Centre (TRAC) from the University of Toronto, Canada agreed to license MedGenome's patented cancer immunotherapy solution OncoPept to develop biomarkers for their drug candidates against immune modulators to treat cancer.

Full Story >>

Are some people genetically programmed to be depressed?

Updated: Jul 21, 2017 09:48 IST     

Washington D.C. [USA], Jul 21 (ANI): It's a sombre thought, but it seems that some of us are born more likely to be depressed.

Full Story >>

Washington D.C. [USA], Jul 21 (ANI): A team of researchers has come up with a new imaging technique that can diagnose cardiac sarcoidosis much more accurately than traditional tests.

Full Story >>

Ahmedabad (Gujarat) [India], July 21 (ANI): Ayurveda is a form of alternative medicine which seeks to treat and integrate body, mind and spirit using a comprehensive holistic approach especially by emphasizing diet, herbal remedies, exercise, meditation, breathing, and physical therapy.

Full Story >>

Washington D.C. [USA], Jul 20 (ANI): When it comes to faring well after chemotherapy, a cancer patient's social interaction matters, according to a recent study.

Full Story >>

New radiotherapy find offers hope to cancer patients

Updated: Jul 20, 2017 10:06 IST     

Washington D.C. [USA], Jul 20 (ANI): An exciting discovery in the cancer treatment is having dramatic results.

Full Story >>

New strategy could yield more effective flu shots

Updated: Jul 20, 2017 09:46 IST     

Washington D.C. [USA], Jul 20 (ANI): A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a recent study.

Full Story >>

Revealed! Best time to sleep to wake up feeling refreshed

Updated: Jul 20, 2017 04:09 IST     

London [UK], July 20 (ANI): The secret of a good night's sleep has finally been unveiled!

Full Story >>

Anxiety drug may help you with fear of social rejection

Updated: Jul 19, 2017 14:22 IST     

Washington D.C. [USA], July 19 (ANI): A team of researchers has found that low doses of anxiety disorder-reducing drug can help highly-anxious people overcome their fear of being over-looked and rejected socially.

Full Story >>

Washington D.C. [USA], July 19 (ANI): Good news! A new technology may help to non-invasively predict children or newborn at risk of an asthma attack.

Full Story >>

Your poor sleep may increase risk of Alzheimer's: Study

Updated: Jul 19, 2017 10:08 IST     

Washington D.C. [USA], July 19 (ANI): Beware! Breathing problems during sleep may be a signal of an increased risk for Alzheimer's disease, warns a study.

Full Story >>

Indian population, carrier of hepatitis B: Study

Updated: Jul 18, 2017 20:01 IST     

New Delhi [India], July 18 (ANI): Viral hepatitis is inflammation and damage of the liver by viruses , most commonly hepatotrophic (predominantly with an affinity for attacking the liver - Hepatitis A , B , C , D , E ) or non hepatotrophic viruses (Generalized involvement of human body with liver as a target tissue seen with Dengue virus , Chikungunya etc.).

Full Story >>

This monsoon, let's be HepAware!

Updated: Jul 18, 2017 18:01 IST     

New Delhi [India], July 18 (ANI): Hepatitis A is mild to the moderate viral disorder of the liver which is affected by the consumption of contaminated food and water. Unfortunately, monsoons are the best time when air/water borne infections are at its peak.

Full Story >>

Washington D.C. [USA], July 18 (ANI): If your grandparents are suffering from dementia, then you can help them by interacting with them about their interests for an hour a week and improve their quality life.

Full Story >>

New Delhi [India], July 17 (ANI): Commemorating its 21st Founder's Day and in an endeavor to promote healthy lifestyle, Pushpawati Singhania Hospital & Research Institute (PSRI) a multi-specialty hospital here organized free health check-up camps and school wellness programme.

Full Story >>

Here's how weekly social hour can help dementia patients

Updated: Jul 17, 2017 11:49 IST     

Washington D.C. [USA], Jul 17 (ANI): Person-centred activities combined with just one hour a week of social interaction can improve quality of life and reduce agitation for people with dementia living in care homes, while saving money, according to a recent study.

Full Story >>

Combo therapy better than drug alone against Alzheimer's

Updated: Jul 17, 2017 11:34 IST     

Washington D.C. [USA], Jul 17 (ANI): Combining a specific care management program with a commonly-prescribed drug for Alzheimer's disease is better at turning back the clock on the ageing brain than medication alone, according to a recent study.

Full Story >>

Washington D.C. [USA], Jul 17 (ANI): Nearly 30 percent of stroke patients are refusing to take life-saving statins because they are worried about the side effects, according to a recent study.

Full Story >>