Washington D.C. [USA], Sept. 6 (ANI
): A recent research shows that
exposure to antibiotics early in life is related to increased risk of
developing allergies in late ages.
In this new research, huge databases were searched for observation and
assessment of the association between antibiotic consumption during
the first two years of life and the risk of eczema or hay fever later
A total of 22 studies (including 394,517 patients) were selected to
study the risk of eczema and 22 studies (including 256,609 patients)
to study the risk of hay fever, with some of these being the same (12
studies including 64,638 patients) studies for both conditions.
The increased risk of eczema due to early life use of antibiotics
varied from 15 percent to 41 percent depending on the type of study
Use of antibiotics in early life also increased the risk of hay fever
in later life by 14 percent to 56 percent again dependent on the type
of study analysed.
Further, the association was stronger if patients had been treated
with two courses compared with one course of antibiotics both for
eczema and for hay fever.
The authors suggest the mechanism behind this effect is the
immunomodulatory effect of antibiotics, and the disruption of the
microorganisms (microbiome) in the gut caused by antibiotics which can
lead to reduce immune responses.
Ahmadizar, the lead author concludes, "Early life exposure to
antibiotics is related to an increased risk of both eczema and hay
fever later in life."
The research was presented at European Respiratory Society (ERS)
International Congress in London. (ANI