Fri, Feb 24, 2017 | updated 10:41 PM IST

Dietary restriction can add years to your life

Updated: Jul 15, 2016 09:23 IST

Washington D.C, Jul 15 (ANI): Boosting lifespan is as simple as limiting your food intake, suggests a new study.

The study from the Sanford Burnham Prebys Medical Discovery Institute (SBP) represents a major advance in understanding how dietary restriction leads to longevity in many species, including humans.

"In this study, we used the small roundworm C. elegans as a model to show that autophagy in the intestine is critical for lifespan extension," said senior author Malene Hansen. "We found that the gut of dietary-restricted worms has a higher than normal rate of autophagy, which appears to improve fitness in multiple ways preserving intestinal integrity and maintaining the animal's ability to move around."

In this study the team wanted to understand how dietary restriction impacts autophagy in the intestine, whose proper function is already known to be important for long life.

"The strain of worms we used, called eat-2, is genetically predisposed to eat less, and they live longer than normal worms, so they provide an ideal model in which to investigate how dietary restriction extends lifespan," said lead author Sara Gelino, adding "We found that blocking autophagy in their intestines significantly shortened their lifespans, showing that autophagy in this organ is key for longevity."

The results led the team to examine how inhibiting autophagy impacts the function of the intestine. They found that while normal worms' gut barriers become leaky as they get older, those of eat-2 worms remain intact. Preventing autophagy eliminated this benefit, which indicates that a non-leaky intestine is an important factor for long life.

"How intestinal integrity relates to longevity is not clearly understood," Hansen commented. "It's possible that the decline in the gut's barrier function associated with normal aging might let damaging substances or pathogens into the body."

The research team also observed that turning off autophagy in the intestine made the slow-eating, long-lived worms move around less.

The study is published in PLoS Genetics. (ANI)

Too much sugar may causes Alzheimer's

Updated: Feb 24, 2017 06:13 IST

London [UK], Feb. 24 (ANI): A diet, high in sugar, could lead to Alzheimers, as a study finds a link between sugar and the brain disease.

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New Delhi [India], Feb. 23 (ANI): A study was conducted in 19 centers over a period of six months to understand the different types of constipation and the causes behind them. One of the key highlights has been that constipation is highly prevalent in cities as compared to the rural areas.

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New Delhi [India], Feb 23. (ANI): Never neglect your kid, if you do not want to subject him to mental health issues!

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Now, you can cure insomnia with placebo: Study

Updated: Feb 23, 2017 06:27 IST

Washington D.C. [USA], Feb. 23 (ANI): Briton researchers have found a simple placebo may really work well to cure insomnia.

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Washington D.C. [USA], Feb. 23 (ANI): Beware! US researchers warned that taking drugs to reduce gastric acid for prolonged periods may lead to serious kidney problems, including kidney failure.

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New Delhi [India], Feb. 22 (ANI): In rarest of its kind, a paediatric surgery performed by doctors at a city-based hospital gave a new lease of life to a newborn, suffering from a life-threatening defect of the alimentary canal.

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Beware! Zika can be a reason for miscarriage

Updated: Feb 22, 2017 14:18 IST

Washington D.C. (USA), Feb. 22 (ANI): Beware to-be mothers! According to a recent study, Zika virus could lead to a greater risk of miscarriage in the early stage of pregnancy.

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Washington D.C. (USA), Feb. 22 (ANI): Women with a rare type of epithelial ovarian or peritoneum cancer, can now take sigh of relief.

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Washington D.C. [USA], Feb. 22 (ANI): Now don't blame those chips and chocolates for you childs extra pounds, as a study says around 35-40 percent of a child's is inherited from their parents.

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Drinking too much may age arteries over time!

Updated: Feb 22, 2017 06:03 IST

Washington D.C. [USA], Feb. 22 (ANI): Excessive boozing over the years might age arteries prematurely, especially in men, putting them at an increased risk for heart disease.

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Chronic knee pain may be treated online

Updated: Feb 21, 2017 06:41 IST

Washington D.C. [USA], Feb. 21 (ANI): A study has found out that an online intervention, combining home exercise and pain-coping skills training, provided substantial clinical benefits for patients suffering from chronic knee pain.

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Washington D.C. [USA], Feb. 21 (ANI): Only exercise is not enough to maintain that figure, which is an after effect of much toil and sweat!

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New Delhi [India], Feb. 20 (ANI): With rising life expectancy, increasingly sedentary lifestyles and surge in incidence of obesity, India is also witnessing a resultant rise in orthopedic problems as a natural corollary.

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Children inherit obesity from parents: Study

Updated: Feb 20, 2017 14:54 IST

Washington D.C. (USA), Feb. 20 (ANI): A study reveals that 35-40 percent of a child's 'Body Mass Index' - how fat or thin they are - is inherited from their parents.

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New Delhi [India], Feb 20. (ANI): Good news for all those lazy-headed not-really-a-cleanliness-freak out there! Scientists have found out that the obsession with hygiene could even be turning some beneficial bacteria found in the human gut into "endangered species".

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New Delhi [India], Feb 20. (ANI): In order to persuade someone to quit smoking, it is the 'emotions' that need to be triggered rather than inciting fear in an individual.

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No difference between good or bad diet: Study

Updated: Feb 20, 2017 05:54 IST

New Delhi [India], Feb 20. (ANI): Ever faced a choice between Brown and white bread?

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Washington D.C. [USA], Feb. 19 (ANI): To boost sustainability of livestock production, a study finds that gene editing - one of the newest and most promising tools of biotechnology - enables animal breeders to make beneficial genetic changes, without bringing along unwanted genetic changes.

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People with ADHD may have smaller brain volume

Updated: Feb 19, 2017 07:09 IST

New Delhi [India], Feb 19. (ANI): In a latest study it has been found out that people diagnosed with attention deficit hyperactivity disorder (ADHD) have smaller brain volume than those without the disorder.

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New Delhi [India], Feb 19. (ANI): What if we tell you that scientists can actually slow down the process of ageing. Sounds too good to be true right?

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