Fri, Mar 24, 2017 | updated 03:48 PM IST

New 'smart' thread paves way for next-gen implantable diagnostics

Updated: Jul 18, 2016 13:18 IST

Washington D.C, Jul 18 (ANI): A team of researchers has invented a smart thread that collects diagnostic data when sutured into tissue.

Researchers led by Tufts University engineers integrated nano-scale sensors, electronics and microfluidics into threads, ranging from simple cotton to sophisticated synthetics, that can be sutured through multiple layers of tissue to gather diagnostic data wirelessly in real time.

The research suggests that the thread-based diagnostic platform could be an effective substrate for a new generation of implantable diagnostic devices and smart wearable systems.

The researchers used a variety of conductive threads that were dipped in physical and chemical sensing compounds and connected to wireless electronic circuitry to create a flexible platform that they sutured into tissue in rats as well as in vitro. The threads collected data on tissue health (e.g. pressure, stress, strain and temperature), pH and glucose levels that can be used to determine such things as how a wound is healing, whether infection is emerging, or whether the body's chemistry is out of balance. The results were transmitted wirelessly to a cell phone and computer.

The three-dimensional platform is able to conform to complex structures such as organs, wounds or orthopedic implants.

"The ability to suture a thread-based diagnostic device intimately in a tissue or organ environment in three dimensions adds a unique feature that is not available with other flexible diagnostic platforms," said corresponding author Sameer Sonkusale.

Sonkusale added, "We think thread-based devices could potentially be used as smart sutures for surgical implants, smart bandages to monitor wound healing, or integrated with textile or fabric as personalized health monitors and point-of-care diagnostics."

"By contrast, thread is abundant, inexpensive, thin and flexible, and can be easily manipulated into complex shapes," said first author Pooria Mostafalu, adding "Additionally, analytes can be delivered directly to tissue by using thread's natural wicking properties."

The study appears in Microsystems and Nanoengineering. (ANI)

New Delhi [India], Mar. 24 (ANI): Continuing its efforts to raise awareness on tuberculosis and its diagnosis, Division of Clinical Microbiology & Molecular Medicine Department of Laboratory Medicine, AIIMS, and BD (Becton Dickinson India) for the third consecutive year organized a symposium today on "challenges in diagnosis and eradication of tuberculosis".

Full Story >>

New Delhi [India], Mar. 24 (ANI): On the solemn occasion of World Tuberculosis (TB) Day, Members of Parliament, policymakers, TB patients, survivors, and citizens of the civil society gathered at India Gate on Thursday, March 23 to pay tribute to the nearly five lakh lives lost due to this disease last year.

Full Story >>

New Delhi [India], Mar. 24 (ANI): Emergence of multi drug resistant TB and complications aggravated by high rates of co-infection with HIV-AIDS has renewed the threat of TB epidemic in India. With widespread prevalence of the infection, children experience a serious risk of contracting Tuberculosis, especially if they are under-nourished.

Full Story >>

New Delhi [India], Mar. 24 (ANI): Tuberculosis can affect any age, caste or class and it is one of the top 10 causes of death across the globe, ranking above HIV and malaria.

Full Story >>

New Delhi [India], Mar. 24 (ANI): Tuberculosis is one of the top 10 causes of death across the globe, ranking above HIV and malaria. According to the World Health Organization (WHO), in 2015, there were 10.4 million new cases of TB worldwide.

Full Story >>

London [UK], Mar. 23 (ANI): Want happy families? Then delay your decision to start a family, as a study suggests, children born to older mother experience have fewer behavioural, social and emotional problems.

Full Story >>

Washington D.C. [USA], Mar. 23 (ANI): For women, stay fit and maintain a healthy weight, as a study finds a higher waist-to-hip ratios increases the risk of ovarian cancer risk by more than a fifth.

Full Story >>

Washington D.C. [USA], Mar. 23 (ANI): A study finds that people who are born blind have heightened sense of hearing, smell and touch, suggesting that their brain "rewires" itself in the absence of visual information to boost other senses.

Full Story >>

New Delhi [India], Mar. 23 (ANI): For those suffering with age-related (degenerative) arthritis of the knee, a stage comes when all the reasonable non-operative options stops working.

Full Story >>

Hepatitis drug can help cut Ebola death rate

Updated: Mar 22, 2017 09:30 IST

Washington D.C. [USA], Mar. 22 (ANI): A class of drugs used to treat hepatitis and some forms of multiple sclerosis has shown promise in treating Ebola.

Full Story >>

Weekend surgery 'not riskier'

Updated: Mar 22, 2017 09:20 IST

Washington D.C. [USA], Mar. 22 (ANI): Day of the week has no impact on the survival chances of people undergoing emergency surgery, a new research has found.

Full Story >>

Washington D.C. [USA], Mar. 22 (ANI): Despite existing prevention methods, transmission of infections with HIV, hepatitis B, syphilis or rubella from mother to child before and during birth as well as in infancy still occur across Europe.

Full Story >>

Changes in blood may spur Alzheimer's disease

Updated: Mar 22, 2017 07:29 IST

Washington D.C. [USA], Mar. 22 (ANI): A recent study has linked changes in the vascular system to Alzheimer's disease.

Full Story >>

Spraying onto broken hearts to heal them

Updated: Mar 22, 2017 06:45 IST

Washington D.C. [USA], Mar. 22 (ANI): A team of scientist has come up with a new method that may make the heart surgeries a history.

Full Story >>

Washington D.C. [USA], Mar. 22 (ANI): With both tourism and casual "hookup" sex on the rise among college-age adults, there's an urgent need for gender-sensitive and age-appropriate sexual health campaigns that are tailored to young women's motivations for taking sexual risks while travelling, a new study has suggested.

Full Story >>

Washington D.C. [USA], Mar. 21 (ANI): Now, detecting a mosquito-borne illness will be as easy as clicking a smartphone app - thanks to a team of scientists.

Full Story >>

Washington D.C. [USA], Mar. 21 (ANI): A team of researchers has shed some light on how infections during pregnancy may interfere with the genes linked to prenatal brain development.

Full Story >>

Soon, a faster way to treat depression

Updated: Mar 21, 2017 16:02 IST

Washington D.C. [USA], Mar. 21 (ANI): A new and faster way to treat depression has come closer to reality - thanks to a team of scientists.

Full Story >>

All you need to know on Colorectal Cancer!

Updated: Mar 21, 2017 08:00 IST

New Delhi [India], Mar. 21 (ANI): Colorectal cancer is also known as colon cancer, bowel cancer. It refers to a cancerous growth, lump or a tumour in the colon and the rectum. It is the second most common cancer, after adenocarcinoma.

Full Story >>

Prevent yourself from chronic kidney disease!

Updated: Mar 21, 2017 07:50 IST

New Delhi [India], Mar. 21 (ANI): Each person normally has two kidneys, which are about the size of a fist and are located on either side of the spine at the level of waist.

Full Story >>