Mon, May 29, 2017 | updated 01:51 AM IST

Soon, a 'needle-free' vaccine for STI Chlamydia

Updated: Jul 20, 2016 13:18 IST      
Soon, a 'needle-free' vaccine for STI Chlamydia

Washington D.C, Jul 20 (ANI): World's first vaccine for an insidious sexual transmitted infection (STI) has come closer to reality in the form of a nose spray.

Researchers at the Michael G. DeGroote Institute for Infectious Disease Research at McMaster have developed the first widely protective vaccine against chlamydia, a common STI that is mostly asymptomatic but impacts 113 million people around the world each year and can result in infertility.

In a study, the team showed that a novel chlamydial antigen known as BD584 is a potential vaccine candidate for the most common species of chlamydia known as Chlamydia trachomatis.

As most C. trachomatis infections are asymptomatic, chlamydia can often go untreated and lead to upper genital tract infections, pelvic inflammatory disease, and infertility. This is why the promise of a vaccine would be extremely beneficial, said co-author David Bulir.

"Vaccine development efforts in the past three decades have been unproductive and there is no vaccine approved for use in humans," said Bulir, adding "Vaccination would be the best way to way to prevent a chlamydia infection and this study has identified important new antigens which could be used as part of a vaccine to prevent or eliminate the damaging reproductive consequences of untreated infections."

BD584 was able to reduce chlamydial shedding, a symptom of C. trachomatis, by 95 per cent. The antigen also decreased hydrosalpinx, another C. trachomatis symptom, which involves fallopian tubes being blocked with serous fluids, by 87.5 percent.

The results look very promising, said senior author James Mahony.

Co-author and McMaster PhD student, Steven Liang, explains, "not only is the vaccine effective, it also has the potential to be widely protective against all C. trachomatis strains, including those that cause trachoma."

"The vaccine would be administered through the nose. This is easy and painless and does not require highly trained health professionals to administer, and that makes it an inexpensive solution for developing nations," he said.

The next step is more testing for effectiveness against different strains of Chlamydia and in different formulations. The study was funded by the Canadian Institutes for Health Research.

The study is published in the journal Vaccine. (ANI)

Soon, an accurate, cheap genetic test for anal cancer

Updated: May 28, 2017 13:56 IST     

Washington D.C. [USA], May 28 (ANI): A new genetic test could be an accurate and inexpensive way to find and treat those at highest risk of anal cancer - a disease with growing incidence in women, men who have sex with men (MSM) and people with HIV.

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Fight against leprosy: Efforts honoured with ICN award

Updated: May 28, 2017 13:44 IST     

New Delhi [India], May 28 (ANI): The International Council of Nurses (ICN) presented its Health and Human Rights Award to Yohei Sasakawa, Chairman of the Nippon Foundation, at the 2017 ICN Congress in Barcelona, Spain, on May 27.

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Higher BMI can cause cardiovascular problems for youngsters

Updated: May 28, 2017 08:56 IST     

Washington D.C. [USA], May 28 (ANI): A recent study shows that higher than normal Body Mass Index (BMI) may cause worse cardiovascular health in those aged as young as 17.

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Probiotics helpful in treating depression: Study

Updated: May 28, 2017 08:36 IST     

Washington D.C. [USA], May 28 (ANI): According to a new study, adults with irritable bowel syndrome (IBS) reported improvements from co-existing depression, when they took a specific pro-biotic than adults with IBS who took a placebo.

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Exposure to diesel pollution ups risk of heart attack

Updated: May 28, 2017 07:10 IST     

Washington D.C. [USA], May 28 (ANI): A word of caution; avoid places with heavy traffic or try to find a different route as a study has warned that exposure to diesel pollution causes heart attack, heart failure and death.

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Statins improves heart structure and function: Study

Updated: May 27, 2017 23:02 IST     

Washington D.C. [USA], May 27 (ANI): Briton researchers have found that group of drugs, which act to reduce levels of cholesterol in the blood, is linked to improved heart structure and its function.

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Rock climbing for three hours a week may treat depression

Updated: May 27, 2017 19:14 IST     

Washington D.C. [USA], May 27 (ANI): A team of researchers have revealed that bouldering, a form of rock climbing performed without the use of ropes or harnesses, for three hours a week may help to treat depression.

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Beware! Recreational cannabis doubles the risk of gum disease

Updated: May 27, 2017 16:56 IST     

Washington D.C. [USA], May 27 (ANI): Beware! A study has warned that frequent recreational use of cannabis, including marijuana, hashish, and hash oil, doubles the risk of gum disease.

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Bengaluru (Karnataka) [India], May 27 (ANI): BGS Gleneagles Global Hospitals, a Parkway Pantai enterprise, successfully pioneered the day care Bone Marrow Transplant (BMT) transplant program for low risk transplants like autologous transplant for multiple myeloma and mini-allo transplant for various hematological disorders.

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New hope for stroke patients with disabilities

Updated: May 27, 2017 11:22 IST     

Washington D.C.[USA], May 27 (ANI): Stroke patients left with disabilities have been offered new hope as scientists have developed mind-controlled device that helps them retrain brains to move paralyzed hands.

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Washington D.C. [USA], May 27 (ANI): According to a new study, people suffering from HIV tend to spend more time in therapy to manage the chronic condition.

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New Delhi [India], May 26 (ANI): Latest robotic surgery may work as a boon for patients suffering from early stage oropharyngeal carcinoma (cancer of the mouth, neck and throat).

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23-year-old suffers severe heart attack due to smoking

Updated: May 26, 2017 16:01 IST     

New Delhi [India], May 26 (ANI): With several reasons attributing to a paradigm shift in the age groups suffering from heart attacks to younger age brackets, tobacco induced cardiac arrests rate as one of the topmost ones.

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New Delhi [India], May 26 (ANI): According to statistics, India has the third largest Muslim population in the world. The month of Ramadan is about to begin and a vast majority of this population will be fasting for a large number of days.

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Frequent recreational weed puts your mouth at risk

Updated: May 26, 2017 08:12 IST     

Washington D.C. [USA], May 26 (ANI): Frequent recreational use of cannabis, including marijuana, hashish, and hash oil, ups the risk of gum disease, a recent study has found.

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Washington D.C. [USA], May 25 (ANI): A study, presented at EuroCMR, says that chemotherapy-induced cardiomyopathy react more on men than women.

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New Delhi [India], May 25 (ANI): Envisioning a leap in emergency care, Aster DM Healthcare on Thursday launched its most novel and unique concept, the 'Aster Emergency' app, which will offer real-time interface between the patient in emergency and a GPS-enabled Aster 'Responder'.

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New Delhi [India], May 25 (ANI-BusinessWireIndia): Everyuth Naturals, a pioneer and a leading skincare brand known for its natural ingredients and effective products has announced the re-launch of its flagship product in the face wash category with-the new improved Everyuth Tulsi Turmeric Face Wash.

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New Delhi [India], May 25 (ANI): A Sutureless Valve Replacement surgery was recently performed on a 78 year old patient by Global Hospitals, Mumbai.

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Suicide rates among people with autism on rise

Updated: May 25, 2017 11:26 IST     

Washington D.C. [USA], May 25 (ANI): According to a recent study, suicide rates among autism patients have reached 'worryingly' high levels.

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