Sat, Feb 25, 2017 | updated 10:23 AM IST

Soon, a 'needle-free' vaccine for STI Chlamydia

Updated: Jul 20, 2016 13:18 IST

Washington D.C, Jul 20 (ANI): World's first vaccine for an insidious sexual transmitted infection (STI) has come closer to reality in the form of a nose spray.

Researchers at the Michael G. DeGroote Institute for Infectious Disease Research at McMaster have developed the first widely protective vaccine against chlamydia, a common STI that is mostly asymptomatic but impacts 113 million people around the world each year and can result in infertility.

In a study, the team showed that a novel chlamydial antigen known as BD584 is a potential vaccine candidate for the most common species of chlamydia known as Chlamydia trachomatis.

As most C. trachomatis infections are asymptomatic, chlamydia can often go untreated and lead to upper genital tract infections, pelvic inflammatory disease, and infertility. This is why the promise of a vaccine would be extremely beneficial, said co-author David Bulir.

"Vaccine development efforts in the past three decades have been unproductive and there is no vaccine approved for use in humans," said Bulir, adding "Vaccination would be the best way to way to prevent a chlamydia infection and this study has identified important new antigens which could be used as part of a vaccine to prevent or eliminate the damaging reproductive consequences of untreated infections."

BD584 was able to reduce chlamydial shedding, a symptom of C. trachomatis, by 95 per cent. The antigen also decreased hydrosalpinx, another C. trachomatis symptom, which involves fallopian tubes being blocked with serous fluids, by 87.5 percent.

The results look very promising, said senior author James Mahony.

Co-author and McMaster PhD student, Steven Liang, explains, "not only is the vaccine effective, it also has the potential to be widely protective against all C. trachomatis strains, including those that cause trachoma."

"The vaccine would be administered through the nose. This is easy and painless and does not require highly trained health professionals to administer, and that makes it an inexpensive solution for developing nations," he said.

The next step is more testing for effectiveness against different strains of Chlamydia and in different formulations. The study was funded by the Canadian Institutes for Health Research.

The study is published in the journal Vaccine. (ANI)

Dietary prebiotics improve sleep: Study

Updated: Feb 25, 2017 07:20 IST

Washington D.C. [USA], Feb. 25 (ANI): Health benefits of probiotics- the "good bacteria" found in fermented foods and dietary supplements- is known to almost all.

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Too much sugar may causes Alzheimer's

Updated: Feb 24, 2017 06:13 IST

London [UK], Feb. 24 (ANI): A diet, high in sugar, could lead to Alzheimers, as a study finds a link between sugar and the brain disease.

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New Delhi [India], Feb. 23 (ANI): A study was conducted in 19 centers over a period of six months to understand the different types of constipation and the causes behind them. One of the key highlights has been that constipation is highly prevalent in cities as compared to the rural areas.

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New Delhi [India], Feb 23. (ANI): Never neglect your kid, if you do not want to subject him to mental health issues!

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Now, you can cure insomnia with placebo: Study

Updated: Feb 23, 2017 06:27 IST

Washington D.C. [USA], Feb. 23 (ANI): Briton researchers have found a simple placebo may really work well to cure insomnia.

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Washington D.C. [USA], Feb. 23 (ANI): Beware! US researchers warned that taking drugs to reduce gastric acid for prolonged periods may lead to serious kidney problems, including kidney failure.

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New Delhi [India], Feb. 22 (ANI): In rarest of its kind, a paediatric surgery performed by doctors at a city-based hospital gave a new lease of life to a newborn, suffering from a life-threatening defect of the alimentary canal.

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Beware! Zika can be a reason for miscarriage

Updated: Feb 22, 2017 14:18 IST

Washington D.C. (USA), Feb. 22 (ANI): Beware to-be mothers! According to a recent study, Zika virus could lead to a greater risk of miscarriage in the early stage of pregnancy.

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Washington D.C. (USA), Feb. 22 (ANI): Women with a rare type of epithelial ovarian or peritoneum cancer, can now take sigh of relief.

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Washington D.C. [USA], Feb. 22 (ANI): Now don't blame those chips and chocolates for you childs extra pounds, as a study says around 35-40 percent of a child's is inherited from their parents.

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Drinking too much may age arteries over time!

Updated: Feb 22, 2017 06:03 IST

Washington D.C. [USA], Feb. 22 (ANI): Excessive boozing over the years might age arteries prematurely, especially in men, putting them at an increased risk for heart disease.

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Chronic knee pain may be treated online

Updated: Feb 21, 2017 06:41 IST

Washington D.C. [USA], Feb. 21 (ANI): A study has found out that an online intervention, combining home exercise and pain-coping skills training, provided substantial clinical benefits for patients suffering from chronic knee pain.

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Washington D.C. [USA], Feb. 21 (ANI): Only exercise is not enough to maintain that figure, which is an after effect of much toil and sweat!

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New Delhi [India], Feb. 20 (ANI): With rising life expectancy, increasingly sedentary lifestyles and surge in incidence of obesity, India is also witnessing a resultant rise in orthopedic problems as a natural corollary.

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Children inherit obesity from parents: Study

Updated: Feb 20, 2017 14:54 IST

Washington D.C. (USA), Feb. 20 (ANI): A study reveals that 35-40 percent of a child's 'Body Mass Index' - how fat or thin they are - is inherited from their parents.

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New Delhi [India], Feb 20. (ANI): Good news for all those lazy-headed not-really-a-cleanliness-freak out there! Scientists have found out that the obsession with hygiene could even be turning some beneficial bacteria found in the human gut into "endangered species".

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New Delhi [India], Feb 20. (ANI): In order to persuade someone to quit smoking, it is the 'emotions' that need to be triggered rather than inciting fear in an individual.

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No difference between good or bad diet: Study

Updated: Feb 20, 2017 05:54 IST

New Delhi [India], Feb 20. (ANI): Ever faced a choice between Brown and white bread?

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Washington D.C. [USA], Feb. 19 (ANI): To boost sustainability of livestock production, a study finds that gene editing - one of the newest and most promising tools of biotechnology - enables animal breeders to make beneficial genetic changes, without bringing along unwanted genetic changes.

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People with ADHD may have smaller brain volume

Updated: Feb 19, 2017 07:09 IST

New Delhi [India], Feb 19. (ANI): In a latest study it has been found out that people diagnosed with attention deficit hyperactivity disorder (ADHD) have smaller brain volume than those without the disorder.

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