Mon, May 29, 2017 | updated 07:40 AM IST

This drug combo helps soft-tissue cancer survival

Updated: Jul 21, 2016 15:07 IST      
This drug combo helps soft-tissue cancer survival

Washington D.C, Jul 21 (ANI): Adding a novel monoclonal antibody therapy to traditional chemotherapy can help make people more likely to survive advanced sarcoma, a lethal soft-tissue cancer, by nearly a year, suggests a recent study.

Findings from a multicenter clinical trial of the combination therapy, led by researchers at Columbia University Medical Center and NewYork-Presbyterian, represent the first appreciable improvement in sarcoma outcomes in decades.

"We estimated from preclinical data that the new drug--olaratumab--might improve survival in these patients by a few months, but the extent of the improvement exceeded everybody's expectations," said study leader Gary K. Schwartz, adding: "While sarcoma remains a fatal disease, we're encouraged that we're on the right track and hope to build on this progress."

If caught early, sarcomas can be treated effectively with surgery. However, if the disease spreads, or metastasizes, treatment with chemotherapy does relatively little to slow disease progression or improve survival. The median survival time after diagnosis of advanced disease is 12 to 16 months.

Schwartz and his colleagues are currently studying other potential drug targets for arresting the progression of soft-tissue sarcomas.

"Sarcomas are complex. There are, in fact, multiple receptors on the cell surface. PDGFR-alpha is just one of the receptors that are overexpressed on sarcoma cells. We now have some ideas about how to combine drugs that block multiple types of these receptors, which will probably be more effective that targeting a single type of receptor," he said.

The study is published online in The Lancet. (ANI)

Soon, an accurate, cheap genetic test for anal cancer

Updated: May 28, 2017 13:56 IST     

Washington D.C. [USA], May 28 (ANI): A new genetic test could be an accurate and inexpensive way to find and treat those at highest risk of anal cancer - a disease with growing incidence in women, men who have sex with men (MSM) and people with HIV.

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Fight against leprosy: Efforts honoured with ICN award

Updated: May 28, 2017 13:44 IST     

New Delhi [India], May 28 (ANI): The International Council of Nurses (ICN) presented its Health and Human Rights Award to Yohei Sasakawa, Chairman of the Nippon Foundation, at the 2017 ICN Congress in Barcelona, Spain, on May 27.

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Higher BMI can cause cardiovascular problems for youngsters

Updated: May 28, 2017 08:56 IST     

Washington D.C. [USA], May 28 (ANI): A recent study shows that higher than normal Body Mass Index (BMI) may cause worse cardiovascular health in those aged as young as 17.

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Probiotics helpful in treating depression: Study

Updated: May 28, 2017 08:36 IST     

Washington D.C. [USA], May 28 (ANI): According to a new study, adults with irritable bowel syndrome (IBS) reported improvements from co-existing depression, when they took a specific pro-biotic than adults with IBS who took a placebo.

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Exposure to diesel pollution ups risk of heart attack

Updated: May 28, 2017 07:10 IST     

Washington D.C. [USA], May 28 (ANI): A word of caution; avoid places with heavy traffic or try to find a different route as a study has warned that exposure to diesel pollution causes heart attack, heart failure and death.

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Statins improves heart structure and function: Study

Updated: May 27, 2017 23:02 IST     

Washington D.C. [USA], May 27 (ANI): Briton researchers have found that group of drugs, which act to reduce levels of cholesterol in the blood, is linked to improved heart structure and its function.

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Rock climbing for three hours a week may treat depression

Updated: May 27, 2017 19:14 IST     

Washington D.C. [USA], May 27 (ANI): A team of researchers have revealed that bouldering, a form of rock climbing performed without the use of ropes or harnesses, for three hours a week may help to treat depression.

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Beware! Recreational cannabis doubles the risk of gum disease

Updated: May 27, 2017 16:56 IST     

Washington D.C. [USA], May 27 (ANI): Beware! A study has warned that frequent recreational use of cannabis, including marijuana, hashish, and hash oil, doubles the risk of gum disease.

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Bengaluru (Karnataka) [India], May 27 (ANI): BGS Gleneagles Global Hospitals, a Parkway Pantai enterprise, successfully pioneered the day care Bone Marrow Transplant (BMT) transplant program for low risk transplants like autologous transplant for multiple myeloma and mini-allo transplant for various hematological disorders.

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New hope for stroke patients with disabilities

Updated: May 27, 2017 11:22 IST     

Washington D.C.[USA], May 27 (ANI): Stroke patients left with disabilities have been offered new hope as scientists have developed mind-controlled device that helps them retrain brains to move paralyzed hands.

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Washington D.C. [USA], May 27 (ANI): According to a new study, people suffering from HIV tend to spend more time in therapy to manage the chronic condition.

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New Delhi [India], May 26 (ANI): Latest robotic surgery may work as a boon for patients suffering from early stage oropharyngeal carcinoma (cancer of the mouth, neck and throat).

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23-year-old suffers severe heart attack due to smoking

Updated: May 26, 2017 16:01 IST     

New Delhi [India], May 26 (ANI): With several reasons attributing to a paradigm shift in the age groups suffering from heart attacks to younger age brackets, tobacco induced cardiac arrests rate as one of the topmost ones.

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New Delhi [India], May 26 (ANI): According to statistics, India has the third largest Muslim population in the world. The month of Ramadan is about to begin and a vast majority of this population will be fasting for a large number of days.

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Frequent recreational weed puts your mouth at risk

Updated: May 26, 2017 08:12 IST     

Washington D.C. [USA], May 26 (ANI): Frequent recreational use of cannabis, including marijuana, hashish, and hash oil, ups the risk of gum disease, a recent study has found.

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Washington D.C. [USA], May 25 (ANI): A study, presented at EuroCMR, says that chemotherapy-induced cardiomyopathy react more on men than women.

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New Delhi [India], May 25 (ANI): Envisioning a leap in emergency care, Aster DM Healthcare on Thursday launched its most novel and unique concept, the 'Aster Emergency' app, which will offer real-time interface between the patient in emergency and a GPS-enabled Aster 'Responder'.

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New Delhi [India], May 25 (ANI-BusinessWireIndia): Everyuth Naturals, a pioneer and a leading skincare brand known for its natural ingredients and effective products has announced the re-launch of its flagship product in the face wash category with-the new improved Everyuth Tulsi Turmeric Face Wash.

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New Delhi [India], May 25 (ANI): A Sutureless Valve Replacement surgery was recently performed on a 78 year old patient by Global Hospitals, Mumbai.

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Suicide rates among people with autism on rise

Updated: May 25, 2017 11:26 IST     

Washington D.C. [USA], May 25 (ANI): According to a recent study, suicide rates among autism patients have reached 'worryingly' high levels.

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