Mon, Jul 24, 2017 | updated 02:04 AM IST

Hormone levels in hair can affect IVF success rate: Study

Updated: Oct 19, 2016 09:28 IST      
Hormone levels in hair can affect IVF success rate: Study

Washington D.C. [USA], Oct. 19 (ANI): A new study has revealed that the levels of a hormone, when measured in hair, can significantly predict the likelihood of pregnancy in women undergoing In Vitro Fertilization (IVF) treatment.

The new study by The University of Nottingham found that elevated levels of the so-called 'stress hormone' cortisol measured in hair were associated with almost a third less chance of conceiving.

This technique enables doctors to measure cumulative hormonal function over the previous three to six months and, as such, provides a more reliable measure of hormonal function compared to other techniques using saliva, blood and urine that measure only short term levels of the hormone.

The findings provide the first proper evidence that long term levels of cortisol, which are affected by many lifestyle factors including diet, exercise, caffeine and most notably stress, may play an important role in determining reproductive outcomes.

Scientists believe that interventions to reduce cortisol prior to infertility treatment could therefore improve outcomes for the many thousands of couples undergoing IVF each year.

A total of 135 women were recruited from NURTURE fertility clinic in Nottingham between December 2012 and April 2014, 60 percent of whom became pregnant following IVF treatment. Salivary cortisol samples were collected over two days, on waking, 30 minutes after waking and at 10 pm at night. Eighty-eight of the women also provided hair samples for the measurement of cortisol.

After analysing both types of cortisol data researchers found that short term salivary cortisol measurements were not related to pregnancy but in contrast the hair cortisol concentrations were.

The findings suggest that 27 percent of the variance in pregnancy outcome was accounted for by hair cortisol concentrations after controlling for other known factors that are linked to IVF success such as age, Body Mass Index (BMI), number of eggs retrieved and the number of eggs fertilised.

Leading the study, researcher Kavita Vedhara said, "Researchers have been interested in the role that cortisol may play in determining reproductive outcomes for some time now, not least because cortisol is typically elevated in relation to stress. There has been ongoing debate within the scientific community about whether or not stress may influence fertility and pregnancy outcomes."

"While these results do not specifically implicate stress they do provide preliminary evidence that long term cortisol levels are associated with a reduced likelihood of conceiving. A range of factors are likely to account for that, stress being one possibility. These findings are clearly compelling but more research is needed to more fully understand the factors that influence cortisol levels in patients undergoing IVF," Vedhara added.

Another scientist Adam Massey added, "We know that many factors will influence the likelihood of IVF success and, at this stage, we do not fully understand all of the factors that influence whether treatment works or not. However, optimising patient's chances of IVF success is key and this research suggests that reducing cortisol in the months prior to treatment may play an important part in conception."

"The good news for patients is that well known lifestyle changes may help to lower cortisol and therefore optimise the likelihood they will get pregnant," Massey added.

This study has been published in Psychoneuroendocrinology. (ANI)

Genetic variation may increase tuberculosis susceptibility

Updated: Jul 23, 2017 10:53 IST     

Washington D.C. [USA], July 23 (ANI): Chinese researchers have found that a single change in a gene may increase the risk of tuberculosis.

Full Story >>

This is your brain on depression

Updated: Jul 22, 2017 13:55 IST     

Washington D.C. [USA], July 22 (ANI): Got the blues? According to a recent study, depression can change the structure of your brain.

Full Story >>

Rush-hour pollution may be more harmful than thought

Updated: Jul 22, 2017 10:57 IST     

Washington D.C. [USA], Jul 22 (ANI): Turns out, rush-hour commuters may be in for a double whammy of pollution exposure.

Full Story >>

TRAC, MedGenome announce Cancer Immunotherapy solution

Updated: Jul 22, 2017 06:24 IST     

New Delhi [India], July 22 (ANI): Toronto Recombinant Antibody Centre (TRAC) from the University of Toronto, Canada agreed to license MedGenome's patented cancer immunotherapy solution OncoPept to develop biomarkers for their drug candidates against immune modulators to treat cancer.

Full Story >>

Are some people genetically programmed to be depressed?

Updated: Jul 21, 2017 09:48 IST     

Washington D.C. [USA], Jul 21 (ANI): It's a sombre thought, but it seems that some of us are born more likely to be depressed.

Full Story >>

Washington D.C. [USA], Jul 21 (ANI): A team of researchers has come up with a new imaging technique that can diagnose cardiac sarcoidosis much more accurately than traditional tests.

Full Story >>

Ahmedabad (Gujarat) [India], July 21 (ANI): Ayurveda is a form of alternative medicine which seeks to treat and integrate body, mind and spirit using a comprehensive holistic approach especially by emphasizing diet, herbal remedies, exercise, meditation, breathing, and physical therapy.

Full Story >>

Washington D.C. [USA], Jul 20 (ANI): When it comes to faring well after chemotherapy, a cancer patient's social interaction matters, according to a recent study.

Full Story >>

New radiotherapy find offers hope to cancer patients

Updated: Jul 20, 2017 10:06 IST     

Washington D.C. [USA], Jul 20 (ANI): An exciting discovery in the cancer treatment is having dramatic results.

Full Story >>

New strategy could yield more effective flu shots

Updated: Jul 20, 2017 09:46 IST     

Washington D.C. [USA], Jul 20 (ANI): A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a recent study.

Full Story >>

Revealed! Best time to sleep to wake up feeling refreshed

Updated: Jul 20, 2017 04:09 IST     

London [UK], July 20 (ANI): The secret of a good night's sleep has finally been unveiled!

Full Story >>

Anxiety drug may help you with fear of social rejection

Updated: Jul 19, 2017 14:22 IST     

Washington D.C. [USA], July 19 (ANI): A team of researchers has found that low doses of anxiety disorder-reducing drug can help highly-anxious people overcome their fear of being over-looked and rejected socially.

Full Story >>

Washington D.C. [USA], July 19 (ANI): Good news! A new technology may help to non-invasively predict children or newborn at risk of an asthma attack.

Full Story >>

Your poor sleep may increase risk of Alzheimer's: Study

Updated: Jul 19, 2017 10:08 IST     

Washington D.C. [USA], July 19 (ANI): Beware! Breathing problems during sleep may be a signal of an increased risk for Alzheimer's disease, warns a study.

Full Story >>

Indian population, carrier of hepatitis B: Study

Updated: Jul 18, 2017 20:01 IST     

New Delhi [India], July 18 (ANI): Viral hepatitis is inflammation and damage of the liver by viruses , most commonly hepatotrophic (predominantly with an affinity for attacking the liver - Hepatitis A , B , C , D , E ) or non hepatotrophic viruses (Generalized involvement of human body with liver as a target tissue seen with Dengue virus , Chikungunya etc.).

Full Story >>

This monsoon, let's be HepAware!

Updated: Jul 18, 2017 18:01 IST     

New Delhi [India], July 18 (ANI): Hepatitis A is mild to the moderate viral disorder of the liver which is affected by the consumption of contaminated food and water. Unfortunately, monsoons are the best time when air/water borne infections are at its peak.

Full Story >>

Washington D.C. [USA], July 18 (ANI): If your grandparents are suffering from dementia, then you can help them by interacting with them about their interests for an hour a week and improve their quality life.

Full Story >>

New Delhi [India], July 17 (ANI): Commemorating its 21st Founder's Day and in an endeavor to promote healthy lifestyle, Pushpawati Singhania Hospital & Research Institute (PSRI) a multi-specialty hospital here organized free health check-up camps and school wellness programme.

Full Story >>

Here's how weekly social hour can help dementia patients

Updated: Jul 17, 2017 11:49 IST     

Washington D.C. [USA], Jul 17 (ANI): Person-centred activities combined with just one hour a week of social interaction can improve quality of life and reduce agitation for people with dementia living in care homes, while saving money, according to a recent study.

Full Story >>

Combo therapy better than drug alone against Alzheimer's

Updated: Jul 17, 2017 11:34 IST     

Washington D.C. [USA], Jul 17 (ANI): Combining a specific care management program with a commonly-prescribed drug for Alzheimer's disease is better at turning back the clock on the ageing brain than medication alone, according to a recent study.

Full Story >>