Thu, May 25, 2017 | updated 04:11 PM IST

TB tricks one's immune system to spread it among others

Updated: Oct 21, 2016 09:09 IST      
TB tricks one's immune system to spread it among others

Washington D.C. [USA], Oct. 21 (ANI): A new study suggests that tuberculosis (TB) tricks the immune system into attacking the body's lung tissue so that the bacteria are allowed to spread to other people.

The concept, as per the University of Southampton research, proposes that current ideas about how tuberculosis develops in patients may be incomplete and that, in fact, infection causes autoimmunity, where the immune system reacts incorrectly to its own tissue.

Tuberculosis kills more people than any other infectious disease, and the causative bacterium, Mycobacterium tuberculosis, is becoming increasingly resistant to antibiotics used to treat the infection.

The Southampton research team conducted a review of published studies and found evidence suggesting that an autoimmunity process develops in TB.

Paul Elkington, who led the project, said, "We are not disputing that the immune system mainly targets the bacteria to fight it off, but we are suggesting that there is more to the story."

"It seems that TB tricks the immune system into damaging our own lung tissue, which therefore makes the person highly infectious through coughing and the TB then spreads by aerosol droplets to other individuals," he said, adding, "There is also a group of patients who develop a range of symptoms, such as eye inflammation, joint inflammation and skin rashes, that are not explained by current TB disease concepts. These symptoms are usually associated with diseases like rheumatoid arthritis and Crohn's disease, which led us to believe autoimmunity plays a key role in the TB disease process."

The researcher highlights that more research is needed to investigate the hypothesis, but if it is proved, the discovery could have major implications for the design of new vaccines and drug treatments.

The Southampton team is now undertaking a programme of work to investigate this new concept. Their approach is to combine the study of cells isolated from TB-infected patients with micro-engineering in 3D in the laboratory to investigate how TB damages the lungs.

The study has been published in Trends in Immunology. (ANI)

New Delhi [India], May 25 (ANI): Envisioning a leap in emergency care, Aster DM Healthcare on Thursday launched its most novel and unique concept, the 'Aster Emergency' app, which will offer real-time interface between the patient in emergency and a GPS-enabled Aster 'Responder'.

Full Story >>

OLX mobile phones category booming steered by Millennials

Updated: May 25, 2017 15:50 IST     

New Delhi [India], May 25 (ANI): With almost 10 million mobile phones, and mobile accessories listed in FY 2016-17 alone, OLX has reinforced its position as the number one online destination for pre-owned mobiles in India.

Full Story >>

New Delhi [India], May 25 (ANI-BusinessWireIndia): Everyuth Naturals, a pioneer and a leading skincare brand known for its natural ingredients and effective products has announced the re-launch of its flagship product in the face wash category with-the new improved Everyuth Tulsi Turmeric Face Wash.

Full Story >>

New Delhi [India], May 25 (ANI): A Sutureless Valve Replacement surgery was recently performed on a 78 year old patient by Global Hospitals, Mumbai.

Full Story >>

Suicide rates among people with autism on rise

Updated: May 25, 2017 11:26 IST     

Washington D.C. [USA], May 25 (ANI): According to a recent study, suicide rates among autism patients have reached 'worryingly' high levels.

Full Story >>

Unhappy, less aware youth prone to alcohol addiction

Updated: May 25, 2017 10:36 IST     

Washington D.C. [USA], May 25 (ANI): Making youth aware of the harms of smoking and drinking could help them steer away from alcohol and cigarettes, suggests a recent study.

Full Story >>

London [UK], May 24 (ANI): Sleep is the easiest thing to forego by hardworking individuals. What we don't realize is, when sleep fails, one's health declines along with the quality of life.

Full Story >>

Washington D.C. [USA], May 24 (ANI): According to a recent study, adequate levels of Vitamin D combined with good sleep can help you manage chronic arthritis and back pain.

Full Story >>

Washington D.C. [USA], May 24 (ANI): You might consider yourself to be a recreational user but could be further along the road to drug addiction than you might have realized, a study suggests.

Full Story >>

Washington D.C. [USA], May 24 (ANI): A recent study shows a multi-protein biomarker blood test to detect breast cancer can potentially reduce use of biopsy up to 67percent.

Full Story >>

Childhood obesity results in early onset of arthritis

Updated: May 24, 2017 09:32 IST     

New Delhi [India], May 7 (ANI): Obesity, which is assuming epidemic proportions among children, is proving too much on their delicate bones and joints.

Full Story >>

Washington D.C. [USA], May 24 (ANI): A team of researchers has found that intestinal fungi, chronic liver damage, increase risk of death for the people with alcohol-related liver disease.

Full Story >>

Here's what dentists can tell about your health

Updated: May 23, 2017 16:46 IST     

Washington D.C. [USA], May 23 (ANI): A recent study has found that by using medical and dental records, researchers can identify what is the cause of disease and how the patients with certain diseases will respond to surgery, medication or other interventions.

Full Story >>

Trying to lose weight? Dieting may not help

Updated: May 23, 2017 15:08 IST     

Washington D.C. [USA], May 23 (ANI): Dieting has a little effect on losing weight, as a study finds that brain cells act as a trigger to prevent us burning calories when food is scarce.

Full Story >>

Washington D.C. [USA], May 23 (ANI): A study finds that late middle-aged people, with a family history and longer version of mitochondrial gene, encountered twice as much memory loss up to 10 years later as someone with a family history and a short version of the gene.

Full Story >>

New Delhi [India], May 22 (ANI): Global nutrition company Herbalife Nutrition undertook a survey on balanced nutrition in 12 markets across Asia Pacific and surveyed more than 6,000 consumers to understand eating habits, exercise and lifestyle habits among them.

Full Story >>

New device could detect inflammation in lungs

Updated: May 22, 2017 15:23 IST     

New Delhi [India], May 22 (ANI): To improve the management of asthma and other respiratory diseases, researchers have created a graphene-based sensor that could lead to earlier detection of looming asthma attacks.

Full Story >>

Clinical trial gives hope to lung disease patients

Updated: May 22, 2017 13:13 IST     

Washington D.C. [USA], May 22 (ANI): A 'game changing' clinical trial has given hope to patients with severe lung disease.

Full Story >>

Even moderate drinking may not keep heart disease at bay

Updated: May 22, 2017 12:29 IST     

Washington D.C. [USA], May 22 (ANI): If you feel having a glass of wine with dinner or moderately consuming any kind of alcohol is going to save you from heart disease, then you might have to think over it again!

Full Story >>

You may blame the polluted air for disrupted sleep!

Updated: May 22, 2017 11:43 IST     

Washington D.C. [USA], May 22 (ANI): If you are not having a sound sleep, then there might be fault in the air!

Full Story >>