Thu, Mar 30, 2017 | updated 12:11 PM IST

Ultrasound treatment does not help in fracture healing: Study

Updated: Oct 26, 2016 13:03 IST

Washington D.C. [US], Oct. 26 (ANI): Low intensity ultrasound after surgical repair of a bone fracture, is a popular treatment to progress recovery, but it does not work, found a large international study led by researchers at McMaster University.

In a clinical trial, the researchers showed no difference in the recovery time when using low intensity pulsed ultrasound (LIPUS) or a placebo device, for patients with a fractured tibia (shinbone).

An accompanying editorial, also published today, suggests "it is time to abandon this ineffective treatment" now that there is strong evidence it doesn't work.

Principal investigator Jason Busse said, "LIPUS is commonly used in North America to accelerate fracture healing -- generating about $250 million in sales a year - but there has been no clear evidence of benefit to support its use."

LIPUS was approved for fracture healing by the U.S. Food and Drug Administration (FDA) in 1994.

Interventions to aid recovery have been popular for tibia fractures since this common fracture heals slowly and often needs further surgery to heal completely.

The international research team conducted a randomized controlled trial of 501 patients at 43 academic trauma centers in North America who underwent surgical repair for a tibia (lower leg) fracture between 2008 and 2012.

The patients were assigned 20-minute daily treatment with either a LIPUS or a placebo device which looked the same.

Everyone involved, including the physicians, data collectors, data analysts and the patients were blind to which treatment was used.

Patients were followed until x-rays showed their fracture was healed, or for 12 months.

There was no difference in time to functional recovery whether patients were treated with the active or placebo device.

There was also no difference in quality of life, return to work, leisure activities, or time to full weight-bearing.

Co-principal investigator Mohit Bhandari, pointed out the importance of ensuring medical devices are supported by evidence.

"LIPUS was approved for fracture healing on the basis of small trials that had important limitations, and they focussed on radiographic healing instead of patient important outcomes," said Bhandari.

"The new trial results establish that LIPUS has no role in managing patients with surgically repaired fractures," he added.

The study was published in the BMJ journal. (ANI)

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