Thu, Mar 30, 2017 | updated 02:16 PM IST

Preggers' urine can predict baby's birth weight

Updated: Nov 04, 2016 11:05 IST

Washington D.C. [USA], Nov. 4 (ANI): When it comes to the baby's birth weight, it can now be predicted, courtesy the mommy to-be's urine, says a new study.

The study by Biomed Central says that urine of a mommy-to-be can help identifying lifestyle interventions that help maintain a healthy birth weight for their baby.

Abnormal fetal growth and birth weight are well-established risk factors for chronic diseases later in life, including the development of type-2 diabetes and obesity.

Mireille Toledano, co-lead author of the research said, "We used a technique called NMR spectroscopy to identify, for the first time, a panel of 10 urinary metabolites in the 3rd trimester of pregnancy that were associated with greater fetal growth and increased birth weight. These metabolites included steroid hormones and important biological building blocks called branched-chain amino acids (BCAAs)."

BCAAs are essential nutrients that are vital during pregnancy as an energy source for the growing fetus. In this study, changes in BCAAs and other metabolites detected in the urine were able to explain 12 percent of the variation seen in birth weight, independent of other known predictors such as parent's own weight and maternal smoking or alcohol intake.

Muireann Coen, co-lead author added, "We found that a 50 percent increase in the mother's level of individual BCAAs equated to a 1-2.4 percent increase in birth weight, or 5-11 grams. When we made comparisons with the lifestyle and environmental exposures of the women in our study we found that the variability between BCAA profiles of individual mothers could be partially explained by levels of physical activity, vitamin D, coffee consumption and smoking exposure, suggesting them to be potential areas of intervention to promote a healthy birth weight."

The research team from Spain at ISGlobal, collected urine samples and lifestyle questionnaire data from over 800 pregnant women, aged 28-33 years old, from two locations in Spain (Gipuzkoa and Sabadell), making it the most comprehensive study of urinary metabolites and fetal weight outcomes to date. The two locations in Spain differed in socio-demographic factors, with women in Gipuzkoa reported to be more educated, from a higher social class and generally healthier than women from Sabadell. This distinction allowed for useful comparisons to be made between women from different backgrounds and different geographical location.

Although the researchers found an association between several lifestyle factors and the metabolomic signature detected in the mother's urine, it is not clear from this study if one is the cause of the other, or if any specific lifestyle factor is associated with an individual metabolite. In observational studies like this it is not possible to rule out other factors and an experimental trial would be needed to test cause and effect. This proof-of principle study highlights the value metabolic profiling of pregnant women could have on personalizing pregnancy plans to improve fetal growth outcomes.

This study has been published in BMC Medicine. (ANI)

Washington D.C. [USA], Mar. 30 (ANI): A new study has suggested that the use of cannabis may impact treatment in women undergoing methadone treatment therapy.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): A recent research has shown that dopamine levels fall during the migraine attacks.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): Making your bones stronger may be as easy as getting injections of peptide, according to a recent study.

Full Story >>

There's a placebo for broken hearts too

Updated: Mar 30, 2017 11:17 IST

Washington D.C. [USA], Mar. 30 (ANI): Turns out, placebos alleviate not only physical pain, but also emotional one.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): A team of researchers has come up with a method for measuring free radicals, which are atoms or groups of atoms with unpaired electrons thought to be partly responsible for making smokers sick, and this could help improve the understanding of the relationship between these substances and health.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): A team of scientists is taking a new tack that could finally yield promising obesity treatments.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): Determining the cause of an ischemic stroke is critical to prevent a second one and now, a new software-based system has offered hope.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): Pain of the hospitalized patients can be eased by immersing them in a virtual reality world, according a recent study.

Full Story >>

Washington D.C. [USA], Mar. 30 (ANI): A team of researchers has come up with a technique that has made tracing hazardous chemicals from fast-food wrappers in the body possible.

Full Story >>

New Delhi [India], Mar. 29 (ANI): Expressing her delight over the passing of Mental Healthcare bill in the Lok Sabha, a therapist thanked Prime Minister Narendra Modi and the elected representatives for taking an initiative for people who are struggling with mental issue.

Full Story >>

Washington.D.C. [USA], Mar. 29 (ANI): A study finds that gastric acid suppression drugs increase the risk of recurrent Clostridium difficile infection - which causes diarrhea and life-threatening inflammation of the colon.

Full Story >>

Ranchi [India], Mar. 28 (ANI): Health Minister of Jharkhand, Ramchandra Chandravanshi has recently claimed that the state has come a long way from the day when Jharkhand was on 18th number among states as far as their healthcare services were concerned. It now stands third in the country, according to an independent survey.

Full Story >>

Washington D.C. [USA], Mar. 28 (ANI): Exposure to fungal product, called aflatoxin, is believed to cause up to 80 percent of liver cancer cases in many parts of the world.

Full Story >>

Washington D.C. [USA], Mar. 26 (ANI): Attention dog lovers! With just six months of training, a German Shepherd can accurately detect breast cancer, a study finds.

Full Story >>

Washington D.C. [USA], Mar. 26 (ANI): A recent study has found that a sleepless night impairs your ability to interpret subtle expressions of happiness and sadness.

Full Story >>

Washington D.C. [USA], Mar. 26 (ANI): When it comes to new moms' workout programs, less is more and so, according to a Kansas State University researcher, new moms may need a bit more flexibility and support to ease back into exercise after giving birth.

Full Story >>

New approach to diagnosing mental disorders

Updated: Mar 26, 2017 10:48 IST

Washington D.C. [USA], Mar. 26 (ANI): A consortium of psychiatrists and psychologists has proposed a new approach to diagnosing mental disorders.

Full Story >>

Washington D.C. [USA], Mar. 26 (ANI): Boosting natural brain opioids may be a better way to treat anxiety, according to a recent study.

Full Story >>

Fecal transplant offers hope for autistic kids

Updated: Mar 26, 2017 09:37 IST

Washington D.C. [USA], Mar. 26 (ANI): In this new era of medical therapy dawning, fecal transplants are poised to help fight a range of conditions, from deadly superbugs to obesity and now, autism is in the firing line.

Full Story >>

Thiruvallur (Chennai) [India], Mar. 25 (ANI): A highly contagious viral disease of cattle and swine, Foot-and-Mouth Disease (FMD) has affected Karani village on the outskirts of Tamil Nadu's Tiruvallur district.

Full Story >>