Thu, Aug 17, 2017 | updated 09:29 AM IST

New imaging technique paves way for better treatment of muscular diseases

Updated: Nov 17, 2016 12:54 IST      
New imaging technique paves way for better treatment of muscular diseases

Washington D.C. [US], Nov. 17 (ANI): According to a recent report published in the Journal of Physiology, scientists have developed a new form of 3D imaging of muscles that would help them in better treatment of muscular diseases and injuries including muscular dystrophy, cerebral palsy, exercise-related injuries, rotator cuff tears, and age-related muscle loss

The imaging technique enabled them to see inside muscle and trace long cables made up of a protein called collagen that are believed to be the culprit behind muscular diseases and injuries.

Muscular conditions, whether hereditary, exercise-induced, or due to normal ageing, can result in stiff, dysfunctional muscles due to changes called fibrosis.

Fibrosis is a roadblock to muscle recovery, and can result in muscle pain, weakness, limited range of motion, or require surgery to treat it.

Researchers used a mouse model of skeletal muscle fibrosis to investigate the structure and function of collagen.

They visualized collagen with conventional 2D and a newly developed method of 3D electron microscopy, mechanically measured muscle stiffness, and quantified the collagen producing cells.

Allison Gillies, the first author of the study, said: "The first time we looked at the 3D imaging results we were surprised--the collagen structures that we saw did not fit the textbook definition of muscle."

Collagen had not been previously known to form long chains in muscle.

Researchers had seen collagen outside muscle cells, but had not determined the level of organization that could only be visualized by 3D microscopy.

When muscles become fibrotic, the number of cables and cells that produce collagen both increase.

These collagen cables and the cells that produce collagen are thus two enticing targets for treating muscle disease and injury.

Commenting on the study, senior author, Lieber said: "Reducing the amount of collagen cables or collagen producing cells in fibrotic muscle may improve muscle function and reduce pain, even obviating the need for corrective surgery." (ANI)

E-cigarette may help people quit smoking: Study

Updated: Aug 17, 2017 07:07 IST     

Washington D.C. [USA], Aug 17 (ANI): Good news! Vaping is safer, as a study recently reveals that adults who use e-cigarettes daily were three times more likely to quit cigarettes compared to those who have never tried e-cigarettes.

Full Story >>

Washington D.C. [USA], Aug 16 (ANI): Older people receiving electric shock therapy, also known as electroconvulsive therapy (ECT), to combat the blues of age will need an additional treatment if insomnia is one of their symptoms, according to a recent study.

Full Story >>

A protein cocktail that helps mend a broken heart

Updated: Aug 15, 2017 12:54 IST     

Washington D.C. [USA], Aug 15 (ANI): A team of researchers has uncovered a novel role for transcription factor Gata4 in reducing the post-heart attack fibrosis.

Full Story >>

You could be binge-watching your way to poor sleep

Updated: Aug 15, 2017 10:16 IST     

Washington D.C. [USA], Aug 15 (ANI): Binge-watching may be fun, but it comes at a price, according to a recent study.

Full Story >>

Is diabetes cure right under our skin?

Updated: Aug 15, 2017 09:47 IST     

Washington D.C. [USA], Aug 15 (ANI): The optimal location to treat type 1 diabetes (T1D) might be just under our skin, according to a recent study.

Full Story >>

Gautam Gambhir pledges to spread awareness for Organ Donation

Updated: Aug 14, 2017 06:08 IST     

New Delhi [India], August 14 (ANI): Indraprastha Apollo Hospitals, in association and cricketer Gautam Gambhir, came together on the occasion of World Organ Donation Day to encourage people to take a pledge for donating organs to save countless lives.

Full Story >>

This memory trick may help older adults boost memory

Updated: Aug 13, 2017 15:42 IST     

Washington D.C. [USA], Aug 13 (ANI): A team of researchers have revealed a helpful strategy that may help older adults improve their memory.

Full Story >>

New Delhi [India], August 13 (ANI): There are a large number of people still waiting for a transplant and it is a fact that these patients will succumb to their ailments due to an insufficient number of organ donors.

Full Story >>

New Delhi [India], August 13 (ANI): Every year, 90% people in need of a critical organ to save their life end up facing death due to unavailability of donors.

Full Story >>

New device can help you take more accurate BP readings

Updated: Aug 13, 2017 05:25 IST     

Washington D.C. [USA], Aug 13 (ANI): A team of researchers has come up with a new device that could improve how systolic blood pressure (BP) is measured.

Full Story >>

E-cigarettes make your heart's ageing clock tick 'faster'

Updated: Aug 13, 2017 03:31 IST     

Washington D.C. [USA], Aug 13 (ANI): A new study has suggested that a single exposure to e-cigarette vapour may be enough to impair vascular function.

Full Story >>

This monsoon, keep fungal infections at bay

Updated: Aug 12, 2017 14:42 IST     

New Delhi [India] August 12 (ANI): Monsoon has been here for a while now, but it's not just the muddy roads and never ending traffic, which is a matter of concern. Monsoon brings with it skin and fungal infection that can be downright uncomfortable for anyone.

Full Story >>

New Delhi [India], August 12 (ANI): There has been a significant increase in the incidence of lifestyle diseases such as diabetes, with low awareness about the cure and control status of ailments linked to it.

Full Story >>

Top 8 radiation sources at your home

Updated: Aug 12, 2017 06:15 IST      By: Pallavi Aman Singh

New Delhi [India], Aug 12 (ANI): That tower, outside your home should concern you and rightly so; but what about the materials and products sitting around your house that could be emitting radiation?

Full Story >>

Using only alternative therapy for cancer ups death risk

Updated: Aug 11, 2017 05:19 IST     

Washington D.C. [USA], Aug 11 (ANI): Patients who choose to receive alternative therapy as treatment for curable cancers instead of conventional cancer treatment have a higher risk of death, according to a recent study.

Full Story >>

When it comes to health, is any job better than no job?

Updated: Aug 11, 2017 03:21 IST     

Washington D.C. [USA], Aug 11 (ANI): People employed in low paying or highly stressful jobs may not actually enjoy better health than those who remain unemployed, according to a recent study.

Full Story >>

Here's why you may want to stop judging your emotions

Updated: Aug 11, 2017 02:14 IST     

Washington D.C. [USA], Aug 11 (ANI): Want to feel the sunshine? Embrace the cloudiness of your darker moods as according to a recent study, feeling bad about feeling bad can make you feel worse.

Full Story >>

You can literally lose sleep over being bullied

Updated: Aug 11, 2017 01:49 IST     

Washington D.C. [USA], Aug 11 (ANI): A good night's sleep may be hard to come by if you are being bullied, according to a recent study.

Full Story >>

New 'sleep switch' find paves way for better insomnia cure

Updated: Aug 11, 2017 01:48 IST     

Washington D.C. [USA], Aug 11 (ANI): A team of researchers has discovered a switch outside the brain that can help insomniacs get their ZZZs back.

Full Story >>

Turns out, you can avoid becoming frail as you age

Updated: Aug 10, 2017 05:50 IST     

Washington D.C. [USA], Aug 10 (ANI): Age-related frailty may be a treatable and preventable health problem, just like obesity, diabetes, and cardiovascular disease, according to a recent study.

Full Story >>