Wed, Feb 22, 2017 | updated 07:07 AM IST

Post trial scientists develop tablet to prevent kidney cancer relapse

Updated: Oct 12, 2016 12:22 IST

Washington D.C [USA], Oct. 12 (ANI): A recent trial demonstrates that consuming oral tablet Sunitinib for one year reduces the likelihood of cancer returning for kidney cancer patients following removal of the

kidney.

Reportedly, it is the first ever preventative treatment to make a difference to kidney cancer patients after surgery.

Patients with locally advanced kidney cancer usually face a 40 to 50 percent chance of a relapse within five years after having an operation to remove their kidney.

The clinical trial of an adjuvant treatment for patients, who have had kidney cancer, has been carried out by an international team of oncology experts.

The results of the trial are likely to change clinical practice worldwide.

Kidney cancer accounts for 129,000 deaths worldwide each year and patients with locally advanced kidney cancer face a 50 percent risk of it returning within five years once they have had the operation to

remove their kidney.

While adjuvant treatments are routinely used on patients with other types of cancer (such as breast and bowel cancer), no such treatment capable of improving outcomes for kidney cancer patients have been developed yet.

This is despite numerous studies being carried out in this field over the past 20 years.

The recent research demonstrates that by taking the oral tablet Sunitinib for one year, patients are able to reduce the likelihood of their cancer returning.

The trial, a randomised double blind test was conducted with 615 people with stage T3 renal cell carcinoma, some of whom were given Sunitinib and some a placebo.

Patients receiving Sunitinib had improved disease free survival versus those given the placebo (6.8 years versus 5.6 years).

Sunitinib is a tried and tested drug which has been used on patients with metastatic (widespread) renal cancer for around eight years.

In the trial, as expected, the incidence of side-effects in patients taking Sunitinib was higher to those taking the placebo but these side effects were manageable and did not lay impact on the patients' quality of life.

The trial was led in the UK by Hardev Pandha and its lead researcher was Alain Ravaud.

"This trial was undertaken with a very well-defined population of patients who are generally at high risk of relapse. For these patients, it has shown that taking a simple tablet makes a significant difference without causing a significant decrease in quality of life. Since Sunitinib is already widely used in patients with metastatic

cancer, clinicians are familiar with the drug and its side-effects, so are well placed to prescribe it to patients," Pandha said.

The results of the trial were presented during the Presidential Address of the ESMO 2016 Congress in Copenhagen. (ANI)

Washington D.C. [USA], Feb. 22 (ANI): Now don't blame those chips and chocolates for you childs extra pounds, as a study says around 35-40 percent of a child's is inherited from their parents.

Full Story >>

Drinking too much may age arteries over time!

Updated: Feb 22, 2017 06:03 IST

Washington D.C. [USA], Feb. 22 (ANI): Excessive boozing over the years might age arteries prematurely, especially in men, putting them at an increased risk for heart disease.

Full Story >>

Chronic knee pain may be treated online

Updated: Feb 21, 2017 06:41 IST

Washington D.C. [USA], Feb. 21 (ANI): A study has found out that an online intervention, combining home exercise and pain-coping skills training, provided substantial clinical benefits for patients suffering from chronic knee pain.

Full Story >>

Washington D.C. [USA], Feb. 21 (ANI): Only exercise is not enough to maintain that figure, which is an after effect of much toil and sweat!

Full Story >>

New Delhi [India], Feb. 20 (ANI): With rising life expectancy, increasingly sedentary lifestyles and surge in incidence of obesity, India is also witnessing a resultant rise in orthopedic problems as a natural corollary.

Full Story >>

Children inherit obesity from parents: Study

Updated: Feb 20, 2017 14:54 IST

Washington D.C. (USA), Feb. 20 (ANI): A study reveals that 35-40 percent of a child's 'Body Mass Index' - how fat or thin they are - is inherited from their parents.

Full Story >>

New Delhi [India], Feb 20. (ANI): Good news for all those lazy-headed not-really-a-cleanliness-freak out there! Scientists have found out that the obsession with hygiene could even be turning some beneficial bacteria found in the human gut into "endangered species".

Full Story >>

New Delhi [India], Feb 20. (ANI): In order to persuade someone to quit smoking, it is the 'emotions' that need to be triggered rather than inciting fear in an individual.

Full Story >>

No difference between good or bad diet: Study

Updated: Feb 20, 2017 05:54 IST

New Delhi [India], Feb 20. (ANI): Ever faced a choice between Brown and white bread?

Full Story >>

Washington D.C. [USA], Feb. 19 (ANI): To boost sustainability of livestock production, a study finds that gene editing - one of the newest and most promising tools of biotechnology - enables animal breeders to make beneficial genetic changes, without bringing along unwanted genetic changes.

Full Story >>

People with ADHD may have smaller brain volume

Updated: Feb 19, 2017 07:09 IST

New Delhi [India], Feb 19. (ANI): In a latest study it has been found out that people diagnosed with attention deficit hyperactivity disorder (ADHD) have smaller brain volume than those without the disorder.

Full Story >>

New Delhi [India], Feb 19. (ANI): What if we tell you that scientists can actually slow down the process of ageing. Sounds too good to be true right?

Full Story >>

New Delhi [India], Feb 19. (ANI): Lefty or righty? Well it was decided when you were still in your mum's womb!

Full Story >>

Dads-to be face greater risk of depression

Updated: Feb 19, 2017 06:53 IST

New Delhi [India], Feb 19. (ANI): Expecting a baby is always a joyous experience for both the mother and the father, however a latest study has found out that fathers-to-be can be at risk of depression symptoms if they feel stressed or are in poor health.

Full Story >>

New Delhi [India], Feb 19. (ANI): Do you find it difficult hearing out people at a noisy bar or a restaurant even though you have passed the hearing test with flying colors? Well, you might be secretly deaf!

Full Story >>

New Delhi [India], Feb 19. (ANI): What if we told you that rice has the potential of carrying arsenic and is more than hazardous to feed it to infants!

Full Story >>

Washington D.C. [USA], Feb. 18 (ANI): Now you can save your kid from surgery, as a study shows that antibiotics may be an effective treatment for acute non-complicated appendicitis in children, instead of surgery.

Full Story >>

Washington D.C. [USA], Feb. 18 (ANI): Attention new mommies, sing lullabies to your new born to feel more connected to your babies, suggests a study.

Full Story >>

Washington D.C. [USA], Feb. 18 (ANI): Cancer patients can improve their quality of life with just 30 minutes of walking, suggests a study.

Full Story >>

New Delhi [India], Feb. 17 (ANI): Birth of a baby may be a sweet moment but changing life style of women is posing 'sweet' challenge to it.

Full Story >>