Mon, May 29, 2017 | updated 05:41 AM IST

Gut bacteria's secretion may help against kidney stone

Updated: Oct 14, 2016 10:56 IST      
Gut bacteria's secretion may help against kidney stone

Washington D.C. [US], Oct. 14 (ANI): In a recent research, scientists have discovered that factors secreted by gut bacteria might help prevent or treat kidney stones.

Kidney stones can pose serious health problems for people and can increase their risks of developing chronic kidney disease and kidney failure.

Oxalate is a small anion that can complex with calcium to form calcium oxalate kidney stones under certain conditions and elevated urinary excretion of oxalate can be an indicator of increased risk.

The intestines play a crucial role in oxalate balance and Oxalobacter formigenes (Of) is an anaerobic bacterium that lives in the large intestine and utilizes oxalate as its exclusive energy source.

Expert Hatim Hassan and his team found that factors secreted by Of can stimulate oxalate transport by human intestinal cells grown in tissue culture.

The team also revealed that the mechanisms of the observed stimulation involve the PKA signalling pathway and a protein transporter called SLC26A6.

Importantly, Of factors reduced urinary oxalate excretion by 32.5 percent in mice by stimulating colonic oxalate secretion.

"Probiotic bacteria have several health benefits; however, the difficulties in determining intestinal bacterial bioavailability and biosafety concerns when administering live probiotics are potential problems facing current probiotics clinical applications. Developing probiotics-derived factors as novel therapeutic agents is an alternative approach that addresses such concerns," Hassan explained.

Adding, "The fact that these factors retain their biological activity and can effectively reduce urinary oxalate excretion in mice indicates their significant potential as novel therapeutic agents, and provides a compelling reason for the aggressive pursuit of their characterization, which is currently underway."

The findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN). (ANI)

Soon, an accurate, cheap genetic test for anal cancer

Updated: May 28, 2017 13:56 IST     

Washington D.C. [USA], May 28 (ANI): A new genetic test could be an accurate and inexpensive way to find and treat those at highest risk of anal cancer - a disease with growing incidence in women, men who have sex with men (MSM) and people with HIV.

Full Story >>

Fight against leprosy: Efforts honoured with ICN award

Updated: May 28, 2017 13:44 IST     

New Delhi [India], May 28 (ANI): The International Council of Nurses (ICN) presented its Health and Human Rights Award to Yohei Sasakawa, Chairman of the Nippon Foundation, at the 2017 ICN Congress in Barcelona, Spain, on May 27.

Full Story >>

Higher BMI can cause cardiovascular problems for youngsters

Updated: May 28, 2017 08:56 IST     

Washington D.C. [USA], May 28 (ANI): A recent study shows that higher than normal Body Mass Index (BMI) may cause worse cardiovascular health in those aged as young as 17.

Full Story >>

Probiotics helpful in treating depression: Study

Updated: May 28, 2017 08:36 IST     

Washington D.C. [USA], May 28 (ANI): According to a new study, adults with irritable bowel syndrome (IBS) reported improvements from co-existing depression, when they took a specific pro-biotic than adults with IBS who took a placebo.

Full Story >>

Exposure to diesel pollution ups risk of heart attack

Updated: May 28, 2017 07:10 IST     

Washington D.C. [USA], May 28 (ANI): A word of caution; avoid places with heavy traffic or try to find a different route as a study has warned that exposure to diesel pollution causes heart attack, heart failure and death.

Full Story >>

Statins improves heart structure and function: Study

Updated: May 27, 2017 23:02 IST     

Washington D.C. [USA], May 27 (ANI): Briton researchers have found that group of drugs, which act to reduce levels of cholesterol in the blood, is linked to improved heart structure and its function.

Full Story >>

Rock climbing for three hours a week may treat depression

Updated: May 27, 2017 19:14 IST     

Washington D.C. [USA], May 27 (ANI): A team of researchers have revealed that bouldering, a form of rock climbing performed without the use of ropes or harnesses, for three hours a week may help to treat depression.

Full Story >>

Beware! Recreational cannabis doubles the risk of gum disease

Updated: May 27, 2017 16:56 IST     

Washington D.C. [USA], May 27 (ANI): Beware! A study has warned that frequent recreational use of cannabis, including marijuana, hashish, and hash oil, doubles the risk of gum disease.

Full Story >>

Bengaluru (Karnataka) [India], May 27 (ANI): BGS Gleneagles Global Hospitals, a Parkway Pantai enterprise, successfully pioneered the day care Bone Marrow Transplant (BMT) transplant program for low risk transplants like autologous transplant for multiple myeloma and mini-allo transplant for various hematological disorders.

Full Story >>

New hope for stroke patients with disabilities

Updated: May 27, 2017 11:22 IST     

Washington D.C.[USA], May 27 (ANI): Stroke patients left with disabilities have been offered new hope as scientists have developed mind-controlled device that helps them retrain brains to move paralyzed hands.

Full Story >>

Washington D.C. [USA], May 27 (ANI): According to a new study, people suffering from HIV tend to spend more time in therapy to manage the chronic condition.

Full Story >>

New Delhi [India], May 26 (ANI): Latest robotic surgery may work as a boon for patients suffering from early stage oropharyngeal carcinoma (cancer of the mouth, neck and throat).

Full Story >>

23-year-old suffers severe heart attack due to smoking

Updated: May 26, 2017 16:01 IST     

New Delhi [India], May 26 (ANI): With several reasons attributing to a paradigm shift in the age groups suffering from heart attacks to younger age brackets, tobacco induced cardiac arrests rate as one of the topmost ones.

Full Story >>

New Delhi [India], May 26 (ANI): According to statistics, India has the third largest Muslim population in the world. The month of Ramadan is about to begin and a vast majority of this population will be fasting for a large number of days.

Full Story >>

Frequent recreational weed puts your mouth at risk

Updated: May 26, 2017 08:12 IST     

Washington D.C. [USA], May 26 (ANI): Frequent recreational use of cannabis, including marijuana, hashish, and hash oil, ups the risk of gum disease, a recent study has found.

Full Story >>

Washington D.C. [USA], May 25 (ANI): A study, presented at EuroCMR, says that chemotherapy-induced cardiomyopathy react more on men than women.

Full Story >>

New Delhi [India], May 25 (ANI): Envisioning a leap in emergency care, Aster DM Healthcare on Thursday launched its most novel and unique concept, the 'Aster Emergency' app, which will offer real-time interface between the patient in emergency and a GPS-enabled Aster 'Responder'.

Full Story >>

New Delhi [India], May 25 (ANI-BusinessWireIndia): Everyuth Naturals, a pioneer and a leading skincare brand known for its natural ingredients and effective products has announced the re-launch of its flagship product in the face wash category with-the new improved Everyuth Tulsi Turmeric Face Wash.

Full Story >>

New Delhi [India], May 25 (ANI): A Sutureless Valve Replacement surgery was recently performed on a 78 year old patient by Global Hospitals, Mumbai.

Full Story >>

Suicide rates among people with autism on rise

Updated: May 25, 2017 11:26 IST     

Washington D.C. [USA], May 25 (ANI): According to a recent study, suicide rates among autism patients have reached 'worryingly' high levels.

Full Story >>