Mon, Jun 26, 2017 | updated 10:59 PM IST

High BMI likely to have negative impact on brain functioning

Updated: Oct 18, 2016 15:23 IST      
High BMI likely to have negative impact on brain functioning

Washington D.C. [US], Oct. 18 (ANI): In a recent research conducted at the University of Arizona, scientists have found that having a higher body mass index (BMI), can negatively impact cognitive functioning in older adults.

"The higher your BMI, the more your inflammation goes up," said Kyle Bourassa, the lead author of the study.

Previous studies also have linked higher BMI to lower cognitive functioning. However, how and why the two are connected was far less clear.

"We saw this effect, but it's a black box. What goes in between? Establishing what biologically plausible mechanisms explain this association is important to be able to intervene later," said Bourassa.

The team analyzed data from the English Longitudinal Study of Aging, which includes over 12 years' worth of information on the health, well-being and social and economic circumstances of the English population age 50 and older.

Using two separate samples from the study, one of about 9,000 people and one of about 12,500, researchers looked at aging adults over a six-year period.

With information about participants' BMI, inflammation and cognition, they found the same outcome in both samples.

"The higher participants' body mass at the first time point in the study, the greater the change in their CRP levels over the next four years. CRP stands for C-reactive protein, which is a marker in the blood of systemic inflammation in your body. Change in CRP over four years then predicted change in cognition six years after the start of the study. The body mass of these people predicted their cognitive decline through their levels of systemic inflammation," he said.

The findings support existing literature linking inflammation to cognitive decline and take it a step further by illuminating the important role of body mass in the equation.

"The findings provide a clear and integrative account of how BMI is associated with cognitive decline through systemic inflammation, but we need to remember that these are only correlational findings. Of course, correlation does not equal causation. The findings suggest a mechanistic pathway, but we cannot confirm causality until we reduce body mass experimentally, then examine the downstream effects on inflammation and cognition," he said.

Adding, "Experimental studies finding whether reducing inflammation also improves cognition would be the gold standard to establish that this is a causal effect."

Cognitive decline is a normal part of aging, even in healthy adults, and can have a significant impact on quality of life.

The current research may provide valuable insights for possible interventions and new research directions in that area.

"If you have high inflammation, in the future we may suggest using anti-inflammatories not just to bring down your inflammation but to hopefully also help with your cognition. Having a lower body mass is just good for you, period. It's good for your health and good for your brain," he concluded.

The study was published in the journal Brain, Behavior and Immunity. (ANI)

Untreated polyarthritis can deform joints permanently

Updated: Jun 26, 2017 13:45 IST     

New Delhi [India], June 26 (ANI): Chikungunya, the bone breaking fever, being one of the reasons for polyarthritis , may become a rampant disorder.

Full Story >>

Education, training needed to help human trafficking victims

Updated: Jun 26, 2017 12:17 IST     

Washington D.C. [USA], Jun 26 (ANI): Knowing a little bit more about human trafficking could help save someone and so, a recent research has highlighted the need for education and training.

Full Story >>

Boozing makes ageing clock tick faster

Updated: Jun 26, 2017 10:57 IST     

Washington D.C. [USA], Jun 26 (ANI): Next time you reach for that glass of whiskey, you may want to rethink as a recent research has revealed that the more alcohol you drink, the more your cells appear to age.

Full Story >>

Improving cancer detection with help of body noise

Updated: Jun 26, 2017 07:40 IST     

Washington D.C. [USA], Jun 26 (ANI): According to a recent research, body's own 'seismic noise' can help improve the cancer detection.

Full Story >>

Wound healing goes up in cigarette smoke

Updated: Jun 26, 2017 07:35 IST     

Washington D.C. [USA], Jun 26 (ANI): When it comes to wound healing, vaping may be better than cigarette smoking, according to a recent research.

Full Story >>

Paracetamol during pregnancy can put unborn boys at risk

Updated: Jun 25, 2017 14:45 IST     

New Delhi [India] June 24, (ANI): Pregnant? You may want to rethink popping those paracetamol pills as a recent study has suggested that doing so can harm the masculinity of your unborn son.

Full Story >>

Excessive texting is bad for your wrists

Updated: Jun 25, 2017 11:48 IST     

New York [US], June 25 (ANI): Texting, the thing we do most with our phones, takes a toll on our health.

Full Story >>

Ozone exposure ups autism odds in at-risk people

Updated: Jun 24, 2017 19:47 IST     

Washington D.C. [USA], Jun 24 (ANI): Elevated exposure to ozone can put individuals with high levels of genetic variation at an even higher risk for developing autism than would be expected by adding the two risk factors together, according to a recent analysis.

Full Story >>

Washington D.C. [USA], June 24 (ANI): People suffering from advanced kidney cancer, we have some good news for you.

Full Story >>

Washington D.C. [USA], June 24 (ANI): In a recent study, leisure activities like going for a walk outside, reading, listening to music and other fun activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer's disease.

Full Story >>

Anti-epilepsy drug to treat Alzheimer's disease?

Updated: Jun 24, 2017 10:09 IST     

Washington D.C. [USA], June 24 (ANI): According to a recent study, the scientists have tested an anti-epileptic drug for its potential impact on the brain activity of patients with mild Alzheimer's disease.

Full Story >>

Take these measures to keep oral cancer at bay

Updated: Jun 23, 2017 16:04 IST     

New Delhi [India], June 23 (ANI): Oral Cancer is one of the most prevalent forms of cancer in India. Evidence suggests that India bears the largest burden of oral cancers in the world, with an incidence of around 11.28 percent in Indian men.

Full Story >>

Don't eat but sleep, to beat office blues!

Updated: Jun 23, 2017 10:59 IST     

Washington D.C. [USA], June 23 (ANI): Stressful day at work leads to binge-eating at night. A new study suggests a good night's sleep can serve as a protecting factor between job stress and unhealthy eating in the evening.

Full Story >>

Washington D.C. [USA], June 23 (ANI): According to a recent clinical trial, intensive blood pressure lowering benefits patients with chronic kidney disease.

Full Story >>

New Delhi, [India], June 22 (ANI): J K Organization, in collaboration with Pushpawati Singhania Hospital and Research Institute Multispecialty Hospital, organized a two-day blood donation camp in New Delhi to collect 4043 units of blood.

Full Story >>

Can your blood group predict heart attack risk?

Updated: Jun 22, 2017 13:12 IST     

New Delhi [India], June 22 (ANI): India is presently witnessing nearly two million heart attacks annually. A heart attack (clinically known as myocardial infarction) is the permanent damage or death of the heart muscles due to lack of oxygen-rich blood. According to reports, heart attack kills one person in every 33 seconds in our country.

Full Story >>

Deficits in attention linked to increased alcohol use

Updated: Jun 22, 2017 13:02 IST     

Washington D.C. [USA], June 22 (ANI): Finding it hard to multi-task? Your frequency of alcohol use could be a reason.

Full Story >>

Healing garden at your place: Homoeopathy speaks

Updated: Jun 22, 2017 13:01 IST     

New Delhi [India], June 22 (ANI): One always aspires to be fit and healthy without taking any medicine. If there will be no stress, infections or any other disturbances, there will be no chance of getting ill. But the real world is exactly opposite. There is no life without challenges.

Full Story >>

Looking for stone removal procedure?

Updated: Jun 22, 2017 11:48 IST     

New Delhi [India], June 22 (ANI): Kidneys help in detoxifying and filtering impurities from the blood. They help us excrete excess toxins and excess water through urine.

Full Story >>

Lack Vitamin D? Your job could be a reason

Updated: Jun 22, 2017 09:35 IST     

Washington D.C. [USA], June 22 (ANI): Stuck behind your office desk for most part of the day? Your nine-to-five job could be a major factor that puts you at high risk of Vitamin D deficiency.

Full Story >>