Fri, Apr 28, 2017 | updated 11:33 PM IST

Japanese Yoshinori Ohsumi wins Nobel prize in medicine

Updated: Oct 03, 2016 15:57 IST      
Japanese Yoshinori Ohsumi wins Nobel prize in medicine

London [UK], Oct. 3 (ANI): Japanese cell biologist Yoshinori Ohsumi has been named the 2016 Nobel laureate for his discoveries on how the body's cells detoxify and repair themselves.

The Japanese cell biologist will receive the prestigious eight million Swedish kronor (£718,000) award for "mechanisms for autophagy", reports the Guardian.

Autophagy is the body's internal recycling program - scrap cells are hunted down and the useful parts are stripped out to generate energy or create new cells. It is a crucial process to prevent cancerous growths, and, by maintaining a healthy metabolism, helps protect against conditions like diabetes.

Disturbances in the autophagy mechanism have been linked to many fatal diseases like the Parkinson's disease, type 2 diabetes, cancer and several age-related disorders. Mutations in autophagy genes can cause genetic disease. Intense research is now underway to develop drugs that can target autophagy in various diseases.

In a series of ground-breaking experiments in the early 1990s, Yoshinori Ohsumi used baker's yeast to identify genes essential for autophagy. He then went on to elucidate the underlying mechanisms for autophagy in yeast and showed that similar sophisticated machinery is used in human cells.

Last year, the prize was shared by three scientists for discoveries that helped doctors fight malaria and infections caused by roundworm parasites. (ANI)

Kathmandu [Nepal], April 28 (ANI): Political Parties in Nepal on Friday discussed holding local level polls in a single phase during an all-party meet held at Prime Minister Pushpa Kamal Dahal's official Baluwatar residence.

Full Story >>

Dhaka [Bangladesh], April 28 (ANI): Bangladesh Police have arrested a person for threatening to blow up the Australian High Commission in Dhaka in an email if it refused to pay an extortion amount of Taka 500,000.

Full Story >>

London police foil second terror plot in last 24 hours

Updated: Apr 28, 2017 18:27 IST     

London [United Kingdom], Apr 28 (ANI): London's Metropolitan Police on Friday confirmed that they had neutralised a second active terror plot in the last 24 hours, with the arrest of six people.

Full Story >>

PML-N threatens to sue Imran Khan over bribe allegations

Updated: Apr 28, 2017 17:59 IST     

Lahore [Pakistan], April 28 (ANI): The Pakistan Muslim League-Nawaz (PML-N) has warned Pakistan Tehreek-e-Insaf (PTI) chairman Imran Khan that it will take legal action for leveling 10 billion rupees bribe allegations on the party leadership allegedly to stay silent in the Panama case.

Full Story >>

Iran summons Pak envoy over terror attack on border guards

Updated: Apr 28, 2017 17:41 IST     

Tehran [Iran] April 28 (ANI): Iran on Friday summoned Pakistan's Ambassador to Tehran, Asif Ali Khan Durrani, to lodge a protest over the terrorist attack on Iranian border guards in which nine soldiers were killed and two others injured.

Full Story >>

Warsaw [Poland], Apr 28 (ANI): Vice President of India M. Hamid Ansari has said that the solution to addressing the gaps and failings of democracy is indeed more democracy.

Full Story >>

Indian American killed during crossfire at U.S. motel

Updated: Apr 28, 2017 16:30 IST     

Memphis [United States], April 28 (ANI): A 56-year-old Indian American man was reportedly gunned down while standing on the balcony of his second floor flat in Memphis, Tennessee.

Full Story >>

Karachi [Pakistan], Apr 28 (ANI): The Pakistan Government has barred foreign tourists from visiting the disputed region of Gilgit-Baltistan without obtaining the no-objection certificate from the Ministry of Interior.

Full Story >>

United Nations, Apr 28 (ANI): The United Nations Security Council (UNSC) will today hold a ministerial briefing to address North Korea's nuclear program and missile launches at the request of the US mission to the UN.

Full Story >>

China asks EU to stop interfering in Hong Kong, Macao affairs

Updated: Apr 28, 2017 12:50 IST     

Beijing [China], April 28 (ANI) : China has urged the European Union (EU) to stop interfering in Hong Kong and Macao affairs after the European Commission and European External Action Service issued their 2016 reports on the Hong Kong Special Administrative Region (SAR) and the Macao SAR.

Full Story >>

Trump to consult with 'friend' Xi before speaking to Taiwan

Updated: Apr 28, 2017 11:54 IST     

New York [USA], Apr 28 (ANI): With Sino-US relations appearing to get cozier with frequent consultations between leaders of the two sides, U.S. President Donald Trump has expressed his desire to consult with Chinese President Xi Jinping before speaking to Taiwan's leadership.

Full Story >>

Geneva [Switzerland], Apr 28 (ANI): First ever Refugee Olympic Team swimmer Yusra Mardini, a Syrian who fled across the Mediterranean, has been appointed as a Goodwill Ambassador for United Nations High Commission for Refugees (UNHCR).

Full Story >>

New Delhi [India], Apr 28 (ANI): Cyprus President Nicos Anastasiades said the European Union (EU) and India should work closely to bring peace, stability and development in Afghanistan.

Full Story >>

Taliban launches operation Mansoori, vows more attacks

Updated: Apr 28, 2017 10:57 IST     

Kabul [Afghanistan], Apr 28 (ANI): The Taliban militants group in Afghanistan has vowed to carry out more terror attacks in the country as it announced the launch of its new spring offensive under the name of Mansoori.

Full Story >>

Islamabad [Pakistan], Apr. 28 (ANI): After China said it wanted to fund the USD eight billion Karachi-Peshawar Railway Line project in Pakistan single-handedly, Islamabad has refused part financing from the Asian Development Bank (ADB).

Full Story >>

Beijing [China], Apr 28 (ANI): China has announced to conduct live-fire drills and test new weapons to counter the Terminal High Altitude Area Defense (THAAD), an anti-missile defense system being deployed in South Korea by the United States.

Full Story >>

Conflict with N. Korea is US' 'biggest worry': Trump

Updated: Apr 28, 2017 09:20 IST     

New York [USA], Apr 28 (ANI) U.S. President Donald Trump has admitted that conflict with North Korea is presently the biggest concern on his plate.

Full Story >>

Moscow [Russia], Apr 28 (ANI): Russian President Vladimir Putin and Japanese Prime Minister Shinzo Abe raised their concern over the deteriorating situation on the Korean Peninsula, saying, it is necessary to restart six-party negotiations on the same.

Full Story >>

Macedonia: Protesters storm parliament, attack MPs

Updated: Apr 28, 2017 05:08 IST     

Washington D.C. [U.S.A.], Apr. 28 (ANI): A large number of demonstrators entered the Macedonian parliament, breaking the police cordon and assaulted the MPs, in protest against the election of a new speaker.

Full Story >>

New Delhi [India], Apr. 28 (ANI): U.S. President Donald Trump, on Thursday, hits out at the opponent Democratic Party accusing them of wanting to shut down the ruling government.

Full Story >>