Tue, Feb 28, 2017 | updated 07:53 PM IST

Could these genes drive you towards booze addiction?

Updated: Aug 05, 2016 11:18 IST

Washington D.C, Aug 5 (ANI): A team of researchers has discovered hundreds of genes and genetic codes that appear to play a role in increasing the desire to drink alcohol.

The study at Indiana and Purdue universities, which used rats carefully bred to either drink large amounts of alcohol or to spurn it, not only reinforces the view that the genetics of alcoholism are important, complex and involve many genes, but also that the sections of the genetic code that regulate the actions of genes are at least as important as the genes themselves.

By using high-alcohol-drinking rat lines, the researchers avoided issues that have made genomic analyses of alcoholism in humans difficult, such as inaccurate family histories of drinking, drinking variability and non-genetic economic, social and cultural factors. Although not identical to humans, the genetics of rats and mice often provide powerful clues to genetic activities in humans.

Conducting complete genome analyses of the two lines of rats, the researchers identified key regions of genetic code known as signatures of selection in 930 genes associated with alcohol preference. The majority of the areas were within single gene regions, often within sections of the genetic code that promote or otherwise regulate the activities of the genes.

"This research highlights that alcoholism in rats has a strong genetic component and is influenced by many hundreds of genes, each with small effects. There is no single gene responsible for alcoholism. However, critical regulatory pathways involving several of the genes discovered were found, suggesting that potential pharmacological solutions may be possible," said co-senior author William M. Muir.

Co-senior author Feng C. Zhou noted that "some of the regulatory pathways included those involved with the brain's ability to make new connections over time in response to new activities or environmental factors, what we call neuronal plasticity. Others included neurological and immune systems involved with stress."

"Predictions of risk of alcoholism might become possible," said Muir, "but will require a large number of genetic markers."

Future research, they said, will include verification of these results through analysis of genetic activity that occurs in response to alcohol drinking and also examination of these newly found genes in humans afflicted with the disease.

The study is published in PLOS Genetics. (ANI)

New clues found for nuclear waste cleanup

Updated: Feb 24, 2017 09:35 IST

Washington D.C. (USA), Feb. 24 (ANI): According to a study, the research being done on the chemistry of technetium-99 has boosted the understanding of the challenging nuclear waste and can lead to better cleanup methods.

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Washington D.C. [US], Feb. 24 (ANI): US researchers have suggested that specially trained dogs can be used to find wide-ranging species that are often threatened, sepecially cheetah in a region of Western Zambia.

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Washington D.C. [USA], Feb. 23(ANI): NASA's Spitzer Space Telescope has revealed the first known system of seven Earth-size planets around a single star. Three of these planets are firmly located in the habitable zone, the area around the parent star where a rocky planet is most likely to have liquid water.

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Noida (Uttar Pradesh) [India], Feb.22 (ANI): Germany's Alexander von Humboldt (AvH) Foundation has handed over equipment worth € 20, 000 to Amity University for accelerating research initiatives.

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Washington D.C. (USA), Feb 21 (ANI): The world's first battery to use only hydronium ions as the charge carrier has been been developed by scientists.

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Washington D.C. (USA), Feb. 21 (ANI): According to a new study, Carnegie's Stephen Elardo and Anat Shahar shows that interactions between iron and nickel under the extreme pressures and temperatures similar to a planetary interior can help scientists understand the period in our Solar System's youth when planets were forming and their cores were created.

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Washington D.C. [USA], Feb. 18 (ANI): To boost breeding of endangered poultry breeds, Briton researchers have come up with gene-editing techniques for the rare breeds to use them as surrogates that cannot produce their own chicks.

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Meet 'Bernardbowen'- the new minor planet

Updated: Feb 18, 2017 07:00 IST

Washington D.C. [USA], Feb. 18 (ANI): In a major development, a team of scientists have officially named a minor planet as 'Bernardbowen' that sits in the asteroid belt between Mars and Jupiter.

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New York [USA], Feb. 17 (ANI): NASA has called on the world to help it in the search for the new ninth planet, as anyone from a kindergartener to a 95-year-old, can participate in their new project to find the not-yet-discovered celestial body.

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Washington D.C. [USA], Feb. 9 (ANI): To cut down the number of traffic fatalities, drive less!

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Washington D.C. [USA], Feb. 8 (ANI): According to an international team of astronomers led by researchers from University Of Cambridge, the Magellanic Clouds, the two largest satellite galaxies of the Milky Way, appear to be connected by a bridge stretching across 43,000 light years.

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Washington D.C. [USA], Jan. 25 (ANI): A team of researchers have discovered prehistoric wolf-sized otter fossils with a large head and a powerful jaw, weighing around 100 pounds, in China's Yunnan province.

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Washington D.C. [USA], Jan. 25 (ANI): A study finds that early identification of hearing loss in newborn due to a disease or physical abnormality by birth may help them in better language outcomes as they grow.

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Chennai [India], Jan.14 (ANI-Businesswire India): While "Jallikattu" seems to be the trending topic of discussion in Tamil Nadu at the moment, a silent revolution envisioned by youth icon and late Former President of India, Dr. APJ Abdul Kalam has quietly gained momentum. Ignite-India is a nation-wide innovation platform for student innovators and young entrepreneurs in high schools and colleges. Founded by International swimmer Agnishwar Jayaprakash in 2014, the organization has designed & hosted 96 Regional Innovation Conferences and 3 National Innovation Conferences across 36 cities in India where students competed to showcased their innovative creations. These innovations were judged based on the practicality, creativity & sustainability by technical experts from diverse fields.

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New Delhi [India], Jan. 13 (ANI): New computer simulations have shown that tiny droplets of sulphuric acid resulted in long-lasting cooling, which was a likely contributor to the death of land-living dinosaurs.

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New human organ in digestive system discovered

Updated: Jan 05, 2017 06:27 IST

New Delhi [India], Jan. 5 (ANI): Scientists have discovered what they are calling a new human organ that exists in the digestive system.

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Washington D.C. [USA], January 4 (ANI): Songbirds divorce, pack up and leave and miss their best chances for successful reproduction, courtesy suburban development.

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How do conch shells have such huge variety?

Updated: Jan 04, 2017 05:52 IST

Washington D.C. [USA], January 4 (ANI): Conch shells and its varied shapes and size have always been something that has captivated the eyes of collectors.

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Washington D.C. [USA], Dec. 31 (ANI): A new study finds that despite English being considered the common language of global science, over 30 percent of new scientific reports are published other languages due to which many major findings have been overlooked.

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