Sat, Aug 19, 2017 | updated 08:48 PM IST

New catalysis find sheds light on how to make safer drugs

Updated: Aug 05, 2016 11:32 IST      
New catalysis find sheds light on how to make safer drugs

Washington D.C, Aug 5 (ANI): A team of researchers' work in catalysis could aid drug development.

Many molecules have a chemical structure that is "chiral" - they come in two forms, each with an arrangement of atoms that are mirror images of each other.

These "right-handed" and "left-handed" arrangements, called enantiomers, are problematic for industries that make pharmaceuticals and agrochemicals.

Proteins and sugars in the human body exist in only one of the two enantiomers. Yet the catalytic reactions involved in making drugs often produce molecules with both the "right-handed" and "left-handed" arrangements.

"The handedness of molecules that we ingest, such as drugs, can behave differently depending on whether they are left- or right-handed, often with catastrophic consequences," said University of Wisconsin - Milwaukee's Wilfred Tysoe.

That means that drugs have to be synthesized to have only one "handedness." Current chiral catalysts that can accomplish this task mix tightly with the reactants, making them difficult to separate afterwards.

The goal is to develop a solid "chiral" catalyst that can easily be separated from its products. New research helps to bring that goal closer to reality. The researchers uncovered what happens on the surface of a solid chiral catalyst that allows the preferential formation of only one enantiomer of a molecule.

The study is published in the journal Nature Communications. (ANI)

New Delhi [India], Aug 19 (ANI): Vijnana Bharati's JNU chapter commenced with a Dr Vikram Sarabhai Memorial lecture, celebrating the National Remote Sensing Day in the university's School of Environmental Sciences (SES).

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Indian researchers discover two new species of earthworm

Updated: Aug 19, 2017 06:57 IST     

New Delhi [India], Aug 19 (ANI): A team of Indian researchers has discovered two new primitive species of earthworm in the Western Ghats mountain ranges in Kerala.

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New Delhi [India], Aug 18 (ANI): Two recent studies have highlighted effective ways of reducing antibiotic consumption without any disadvantage for patients.

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Japan introduces solar heat-blocking pavements

Updated: Aug 17, 2017 14:10 IST     

Tokyo [Japan], Aug.16 (ANI): The host city of Olympic and Paralympic Games in 2020, Tokyo is working on heat blocking methods during the summer.

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New Delhi [India], August 17 (ANI): The Fortis Foundation recently launched two charitable medical dispensaries at the Anubhavi Ashram in Haridwar, Uttarakhand and at the Aggarwal Dharamshala in New Delhi.

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Nagpur (Maharashtra) [India], Aug.15 (ANI): The public sector Oil and Natural Gas Coroporation (ONGC) has extended a support of Rs 100 crore to turn the vision of affordable world class cancer care facilities in Central India into reality.

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Are tidally-locked exoplanets more common than believed?

Updated: Aug 15, 2017 10:16 IST     

Washington D.C. [USA], Aug 15 (ANI): There's a possibility for a lot more exoplanets to be tidally locked, according to new research.

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Robots lend a helping hand to esophageal surgeons

Updated: Aug 13, 2017 05:25 IST     

Washington D.C. [USA], Aug 13 (ANI): Robots are no longer just useful tools to make life easy and convenient; turns out, some of them can offer key advantages in esophageal surgeries.

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Are USB connections putting your data at risk?

Updated: Aug 11, 2017 04:21 IST     

Washington D.C. [USA], Aug 11 (ANI): Turns out, USB connections, the most common interface used globally to connect external devices to computers, make snooping easy.

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Turns out, you can catch 'Science' bug from peers

Updated: Aug 10, 2017 07:17 IST     

Washington D.C. [USA], Aug 10 (ANI): According to a recent study, developing an interest in Science as is simple as sitting next to a bunch of students fascinated by the topic.

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Washington D.C. [USA], Aug 9 (ANI): During a walk near a reservoir in a small Japanese town, amateur collectors made the discovery of their lives - the first and oldest fossil bird ever identified in their country.

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Ocean's fastest shark at risk of being 'overfished'

Updated: Aug 09, 2017 01:46 IST     

Washington D.C. [USA], Aug 9 (ANI): Overfishing is putting the ocean's fastest shark at risk, according to a recent research.

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20-month-olds can understand difference between two languages

Updated: Aug 08, 2017 07:12 IST     

Washington D.C. [USA], Aug 8 (ANI): Are two languages at a time too much for the infant mind? According to a recent study, babies as young as 20 months can understand a lot more than you'd think.

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Washington D.C. [USA], August 7 (ANI): Researchers have developed a learning method to change cognitive function by manipulating connections in the brain.

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Kicking butts to the curb

Updated: Aug 07, 2017 00:57 IST     

Washington D.C. [USA], Aug 7 (ANI): Cigarette butts are more than mere litter and now, a team of scientists has found a way to pave over the big problem.

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Desert tortoises can't take heat of roadside fencing

Updated: Aug 06, 2017 13:55 IST     

Washington D.C. [USA], August 6 (ANI): US researchers have revealed that roadside fencing, which is meant to help desert tortoise, can actually overheat them leading to their death.

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Scientists unveil how brain works with the help of magic

Updated: Aug 02, 2017 14:58 IST     

Washington D.C. [USA], August 2 (ANI): To tap into brain's 'out-of-the box' thinking, scientists are now relying on magic tricks and illusions.

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Climate change could put rare bat species at greater risk

Updated: Aug 02, 2017 13:52 IST     

New Delhi [India], Aug 02 (ANI): An endangered bat species with a UK population of less than 1,000 could be further threatened by the effects of global warming, according to a new study led by the University of Southampton.

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London [UK], July 31 (ANI): If you are tired of trying every means to fight obesity, then this new discovery might help you to rethink.

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Climate change may cause more rain, nitrogen runoff

Updated: Jul 29, 2017 11:36 IST     

Washington D.C. [USA], July 29 (ANI): An intensifying water cycle will likely cause dramatic increases - nearing 20 percent by 2100 - in the amount of nitrogen runoff in the U.S., according to a new study.

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