Diabetes may up stroke risk in men

   Mar 26, 1:22 pm

Washington, March 26 (ANI): Men with type 2 diabetes treated with insulin without a history of cardiovascular disease (CVD) were at higher risk for major cardiovascular events (e.g., death, heart attack, stroke) compared with men who had a history of CVD, researchers have revealed.

Using data from the global REACH Registry, researchers at Brigham and Women's Hospital (BWH) evaluated the magnitude of risk of diabetes mellitus on cardiovascular events in both men and women.

Risk was estimated in men and women separately independent of patient age, ethnicity, and other cardiovascular risk factors.

Among the 64,000 eligible REACH patients, the four-year risk of major cardiovascular events (death, heart attack or stroke) increased incrementally in patients with diabetes treated with diet only, oral diabetes medications or insulin.

Male patients with type 2 diabetes treated with insulin but without prior CVD were a particular high-risk group, with an accelerated rate of new cardiovascular events compared to their female counterparts.

For instance, men with diabetes taking insulin had a 16 percent rate of major cardiovascular events over four years. Whereas, men with prior CVD without diabetes had a lower rate for these cardiovascular events, similar to women with diabetes taking insulin and women without diabetes but with prior CVD (about 13 percent).

The researchers concluded that men with diabetes taking insulin had a 70 percent increased risk for a first cardiovascular event compared to men with a known history of CVD having a recurrent event.

In addition, men with diabetes taking insulin were at a 40 percent higher risk than women.

Lower-risk patients (those with diabetes not taking insulin) and very high-risk patients (those with both diabetes and CVD) had no apparent gender-risk differences.

"These findings suggest that both men and women with diabetes with severe insulin resistance (those patients requiring insulin) are at high risk for cardiovascular events, as high risk as patients who already have established cardiovascular disease," said Jacob Udell, MD, Cardiovascular Division, BWH Department of Medicine, and lead study investigator.

"Given that the number of patients diagnosed with type 2 diabetes requiring insulin continues to increase, these patients require diligent cardiovascular risk factor management to potentially avoid a first cardiovascular event," he noted.

The study was presented at the American College of Cardiology 2012 Annual Scientific Session, March 24 to 26 in Chicago. (ANI)

Why some toddlers stare at faces rather than objects Oct 24, 3:53 pm
London, Oct 24 (ANI): In a new study, scientists have pointed to the fact that an infant's preference for a person's face, rather than an object, was associated with lower levels of callous and unemotional behaviors in toddlerhood.
Full Story
Exposure to sunshine slows weight gain, diabetes Oct 24, 12:26 pm
Washington, Oct 24 (ANI): A new study has revealed that exposure to moderate amounts of sunshine may slow the development of obesity and diabetes.
Full Story
How mindfulness can help protect your heart Oct 24, 11:42 am
Washington, Oct 24 (ANI): A new study has revealed that mindfulness, that is paying more attention to the feelings and experiences in the present moments, can help people protect their heart.
Full Story
Ebola death toll likely to exceed 90000 by December in Montserrado: Lancet Oct 24, 10:21 am
Washington, Oct 24 (ANI): A new study has revealed that the death toll from Ebola could top 90,000 by December in Montserrado Africa.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY