Dieting at time of conception may up obesity and diabetes risk of babies

   Apr 2, 10:07 am

Washington, Apr 2 (ANI): Twins and babies of mothers who diet around the time of conception and in early pregnancy, may be more vulnerable to obesity and type 2 diabetes throughout their lives, a new study has revealed.

This study provides exciting insights into how behaviour can lead to epigenetic changes in offspring related to obesity and disease.

"This study may provide a new understanding of why twins can develop diabetes," said Anne White, Ph.D., study author from the Faculty of Life Sciences at the University of Manchester in Manchester, UK.

"It also suggests that dieting around the time a baby is conceived may increase the chance of the child becoming obese later in life."

To make this discovery, White and colleagues conducted experiments involving sheep to investigate twin pregnancies and the effects of altering nutrition around the time of conception and early pregnancy .

Specifically, scientists examined the brain tissue of foetal sheep before birth and found that there were changes in the genes that control food intake and glucose levels that may lead to obesity and diabetes.

These findings are unique because the differences found in the genes are not inherited changes in the DNA sequence, but rather, epigenetic changes with alterations in the structure of the DNA and its associated proteins, histones, which affects the way that genes can behave in later life.

"This study shows that expecting mothers have to walk a really fine line when it comes to diet and nutrition," said Gerald Weissmann, M.D., Editor-in-Chief of the journal.

"It also shows that epigenetics is the 'new genetics': both our DNA and the histones in which it is wrapped are susceptible to binge eating and dieting-we are what our mothers ate," Weissmann added.

The study has been published online in the FASEB Journal. (ANI)

Adults eat 92 pc of what they put on their plate Jul 23, 4:25 pm
Washington, July 23 (ANI): A new study has revealed that the average adult eats 92 percent of whatever he or she puts on his/her plate.
Full Story
Parent's death in childhood may increase kid's mortality risk in adulthood Jul 23, 3:31 pm
Washington, July 23 (ANI): A new study has revealed that individuals who have lost either of their parents during childhood, have 50 percent greater risk of mortality risks in their adulthood than those unexposed to parental death.
Full Story
Sense of smell is 'no friend' for asthmatics Jul 23, 3:31 pm
Washington, July 23 (ANI): A new study has revealed that simply believing that scents and fragrances are potentially harmful could do more damage to the asthmatics people than expected.
Full Story
Connection between age and memory decline revealed Jul 23, 3:31 pm
Washington, July 23 (ANI): A new study has revealed the molecular mechanisms of memory decline with age, using latest high-throughput proteomics and statistical methods.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY