Soy protein may help ease symptoms of fatty liver disease

   Apr 23, 11:24 am

Washington, April 23 (ANI): A diet containing soy protein may significantly reduce fat accumulation and triglycerides in the livers of obese persons, say researchers.

University of Illinois scientists have also discovered why it happens: soy restores partial function of that organ's key signalling pathway.

"Almost a third of American adults have fatty liver disease, many of them without symptoms. Obesity is a key risk factor for this condition, which can lead to liver failure," said Hong Chen, a U of I assistant professor of food science and human nutrition.

Fat is metabolized in the liver, and in obese persons, the transport of fat to adipose tissue can slow down to the point that the liver becomes a dumping ground for excess fat, she said.

"When fat accumulates in an organ that's not supposed to store fat-like the liver, that organ's vital function can be dangerously compromised," she noted.

Adding soy protein, in such sources as tofu and soy yogurt, appears to alleviate some of the stress on fatty livers, she said.

Chen's study compared fat accumulation in the livers of lean and obese rats, which were assigned to either a diet containing casein, a milk-based protein, or a diet containing soy protein isolate, for 17 weeks after weaning. The researchers found that diet had no effect on the liver profiles of lean animals.

But obese rats fed soy showed a 20 percent reduction in triglycerides and overall fat accumulation in the liver, leading Chen to believe that soy protein could be used to alleviate the symptoms of fatty liver disease.

Further, the scientists discovered that soy protein isolate partially restored the Wnt/beta-catenin signaling pathway, a crucial player in fat metabolism.

"In many obese persons, there's a sort of traffic problem, and when more fat can make its way out of the liver, there is less pressure on that organ," she said.

The scientists verified the involvement of this pathway by doing in vitro cell culture studies. (ANI)

High-intensity workouts work better against diabetes than lower counterparts Mar 3, 2:57 pm
Washington, Mar 3 (ANI): As per a new study, both low intensity and high intensity workouts are effective for weight loss, but higher intensity workouts may do a better job of decreasing blood sugar levels.
Full Story
Easy-to-obtain 'oral swab' samples can be game changer for TB control Mar 3, 2:16 pm
Washington, Mar 3 (ANI): A team of researchers has developed new approach to diagnosing tuberculosis (TB) with easy-to-obtain oral swab samples.
Full Story
Many 60-65-yr-old women may still have 'troublesome' hot flashes Mar 3, 1:40 pm
Washington, Mar 3 (ANI): As per a new study, some 40 percent of women 60 to 65 years old still have hot flashes, out of which many have occasional and mild ones, but for some, they remain really troublesome.
Full Story
India's first Centre for Excellence in Robotics opened in Kochi Mar 3, 12:52 pm
Kochi (Kerala), Mar.3 (ANI): Asia-Pacific's first Centre for Excellence in Robotics in medical sector was formally opened by Kerala Chief Minister Oomen Chandy on Monday.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY