Rulebook on breast cancer rewritten

   Apr 19, 11:21 am

London, Apr 19 (ANI): Scientists have identified new breast cancer genes that could revolutionise treatment for thousands of women.

Researchers at the BC Cancer Agency and University of British Columbia have reclassified the disease into 10 completely new categories based on the genetic fingerprint of a tumour.

Many of these genes could offer much-needed insight into breast cancer biology, allowing doctors to predict whether a tumour will respond to a particular treatment.

Whether the tumour is likely to spread to other parts of the body or if it is likely to return following treatment.

The study is the largest global study of breast cancer tissue ever performed and the culmination of decades of research into the disease.

In the future, this information could be used by doctors to better tailor treatment to the individual patient.

The team at the BC Cancer Agency, in collaboration with Cancer Research UK's Cambridge Research Institute and Manitoba Institute of Cell Biology at University of Manitoba, analyzed the DNA and RNA of 2,000 tumour samples taken from women diagnosed with breast cancer between five and 10 years ago.

The sheer number of tumours mapped allowed researchers to spot new patterns in the data.

The new discovery identified genes that were previously unknown to be linked to breast cancer and made it clear that breast cancer is an umbrella term for what really is a number of unique diseases.

Till now, breast cancer had been classified into four subgroups.

"This won't affect women diagnosed today. But in the future, patients will receive treatment targeted to the genetic fingerprint of their tumour," the Daily Express quoted Professor Carlos Caldas, senior group leader at the charity's Cambridge Research Institute, as saying.

"We've moved from knowing what a breast tumour looks like to pinpointing its molecular anatomy. Eventually we'll know which drugs it will respond to.

"The next stage is to discover how tumours in each subgroup behave - for example, do they grow or spread quickly?" Prof Caldas added.

The study has been recently published in the international journal Nature. (ANI)

Blocking this gene cuts excessive fat, finds study Jul 30, 12:55 pm
Washington DC, July 30 (ANI): Scientists have found that it is possible to reduce fat by blocking the expression of a certain gene in patients.
Full Story
ICAR lab artificially breeds milkfish for first time in India Jul 29, 4:28 pm
Chennai, July 29 (ANI): For the first time in India, Chennai-based Central Institute of Brackishwater Aquaculture (CIBA) succeeded in artificially breeding milkfish (Chanos chanos), locally known as "Paal Kendai" or "Poo Meen". Milkfish has the ability to grow in brackish water, seawater and even adapts to freshwater conditions.
Full Story
8-year-old receives world's first double hand transplant Jul 29, 2:22 pm
Washington DC, July 29 (ANI): Surgeons from the Children's Hospital of Philadelphia and Penn Medicine have completed the world's first double hand transplant on an 8-year-old child.
Full Story
Life on Earth probably started as a hiccup rather than roar Jul 29, 1:18 pm
Washington DC, July 29 (ANI): A new research has looked into the origins of Earth and claimed that nearly 4 billion years ago, life on the planet probably started as a hiccup rather than a roar.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY