New 'Achilles' heel' in fungus that causes dandruff identified

   Apr 26, 1:05 pm

Washington, Apr 26 (ANI): Research on the fungus that ranks as one cause of dandruff is directing scientists towards a much required new treatment for the condition's flaking and itching.

Claudiu T. Supuran and colleagues explain that dandruff involves an excessive shedding of dead skin cells from the scalp.

In people without dandruff, it takes about 30 days for a crop of new skin cells to mature, die and shed. In people with dandruff, it may take only 2-7 days.

Irritation by the scalp -dwelling fungus Malassezia globosa (M. globosa) is one cause of dandruff.

Shampoos and other dandruff treatments contain anti-fungal agents, but researchers say that new medicines are badly needed since the two existing compounds are not very effective at preventing and treating dandruff.

In the quest for a better treatment, Supuran's group identified an enzyme in M. globosa that is essential for the fungus's growth.

Tests showed that sulfonamides, a family of existing antibiotic medicines, were more effective in preventing the fungus's growth than ketoconazole, a widely used anti-fungal medicine that is an ingredient in certain dandruff treatments.

As a result of the study, the scientists believe that the enzyme is a prime target for developing better anti- dandruff medicines.

The study has been published in ACS' Journal of Medicinal Chemistry. (ANI)

6,000-yr-old Mesolithic encampment found at Stonehenge dig Dec 21, 12:05 pm
London, Dec. 21 (ANI): Researchers have recently discovered the earliest 6,000-year-old Mesolithic encampment at Stonehenge.
Full Story
Compulsive habits may be product of brain running amuck Dec 21, 10:48 am
Washington, Dec 21 (ANI): A new study has revealed that misfiring of the brain's habit control system may be behind the compulsions in obsessive-compulsive disorder (OCD).
Full Story
Family's criticism over weight makes women gain more pounds Dec 21, 9:38 am
Washington, Dec 21 (ANI): A new study claims that women whose loved ones criticize their weight tend to gain more pounds.
Full Story
How Champagne bubbles can address world's future energy needs Dec 20, 5:28 pm
Washington, Dec 20 (ANI): A new study has shed light on champagne bubbles and examined that it may help address the world's future energy needs.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY