New 'Achilles' heel' in fungus that causes dandruff identified

   Apr 26, 1:05 pm

Washington, Apr 26 (ANI): Research on the fungus that ranks as one cause of dandruff is directing scientists towards a much required new treatment for the condition's flaking and itching.

Claudiu T. Supuran and colleagues explain that dandruff involves an excessive shedding of dead skin cells from the scalp.

In people without dandruff, it takes about 30 days for a crop of new skin cells to mature, die and shed. In people with dandruff, it may take only 2-7 days.

Irritation by the scalp -dwelling fungus Malassezia globosa (M. globosa) is one cause of dandruff.

Shampoos and other dandruff treatments contain anti-fungal agents, but researchers say that new medicines are badly needed since the two existing compounds are not very effective at preventing and treating dandruff.

In the quest for a better treatment, Supuran's group identified an enzyme in M. globosa that is essential for the fungus's growth.

Tests showed that sulfonamides, a family of existing antibiotic medicines, were more effective in preventing the fungus's growth than ketoconazole, a widely used anti-fungal medicine that is an ingredient in certain dandruff treatments.

As a result of the study, the scientists believe that the enzyme is a prime target for developing better anti- dandruff medicines.

The study has been published in ACS' Journal of Medicinal Chemistry. (ANI)

Asymmetrical breasts can play havoc with teens' emotional health Nov 25, 5:14 pm
Washington, Nov 25 (ANI): A new study has revealed that differences in breast size have a significant mental health impact in adolescent girls, affecting self-esteem, emotional well-being, and social functioning.
Full Story
New terahertz radiation device can help make public spaces safer than ever Nov 25, 4:32 pm
Washington, Nov 25 (ANI): Researchers have recently created a compact terahertz radiation source that can help make public spaces safer than ever.
Full Story
How garlic and broccoli help fight cancer Nov 25, 1:06 pm
Washington, Nov 25 (ANI): A new study has revealed that selenium compound that is naturally found in garlic and broccoli boosts immune system to fight against cancer.
Full Story
Gene that helps reducing stroke risk found Nov 25, 12:49 pm
Washington, Nov 25 (ANI): A gene that reduces the risk of stroke in young and middle-aged adults has been discovered.
Full Story
Comments

LATEST STORIES
TOP VIDEO STORIES
PHOTO GALLERY