'Deep sleep' turns on puberty

Washington, September 14 (ANI): Slow-wave sleep or 'deep sleep' is intimately involved in the complex control of the onset of puberty, a new study has suggested.

The many changes that occur in boys and girls during puberty are triggered by changes in the brain.

Previous studies have shown that the parts of the brain that control puberty first become active during sleep, but the present study shows that it is deep sleep, rather than sleep in general, that is associated with this activity.

"If the parts of the brain that activate the reproductive system depend on deep sleep, then we need to be concerned that inadequate or disturbed sleep in children and young adolescents may interfere with normal pubertal maturation," Natalie Shaw, lead researcher from Harvard, said.

"This is particularly true for children who have been diagnosed with sleep disorders, but may also have more widespread implications as recent studies have found that most adolescents get less sleep than they require," she said.

In the study, researchers examined pulses of luteinizing hormone (LH) secretion in relation to specific sleep stages in children ages 9-15. LH is essential for reproduction and triggers ovulation in females and stimulates the production of testosterone in males.

They found that the majority of LH pulses that occur after sleep are preceded by deep sleep suggesting that deep sleep is intimately involved in pubertal onset.

The study has been accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM). (ANI)