3 cups of coffee a day keep HIV death risk at bay

ANI | Updated: Sep 26, 2017 15:46 IST

3 cups of coffee a day keep HIV death risk at bay .

Washington, Drinking at least three cups of coffee and not smoking daily may half the risk of mortality in patients infected by both human immunodeficiency virus HIV and hepatitis C virus HCV .

Patients infected by both HIV and HCV are at specific risk of end-stage liver disease and greater risk of cardiovascular diseases and cancer .

According to researchers, HIV-HCV co-infected patients, drinking at least three cups of coffee each day halved the risk of all-cause mortality .

In the general population, drinking three or more cups of coffee a day has been found to be associated with a 14 percent reduction in the risk of all-cause mortality .

In addition, HIV infection accelerates the progression of chronic hepatitis C to fibrosis and development of cirrhosis and end-stage liver disease .

"This is a very exciting time for HCV research as a cure that can eradicate the virus is now available for all patients," explained lead investigator Dominique Salmon-Ceron from Universite Paris Descartes, Paris .

Coffee is known to have anti-inflammatory and liver-protective properties .

This is probably due to the properties of polyphenols contained in coffee that can protect the liver and also reduce inflammation .

The team used data from a five-year follow-up of 1,028 HIV-HCV co-infected patients .

At enrolment, one in four patients reported drinking at least three cups of coffee daily .

Over the five years, 77 deaths occurred, almost half attributable to hepatitis C .

However, the mortality risk was 80 percent lower in those who were cured of hepatitis C .

Further analysis showed that drinking at least three cups of coffee daily was associated with a 50 percent reduction in mortality risk even after taking into account HCV clearance, HIV- and HCV-related factors, and other sociobehavioral factors, such as having a steady partner and not smoking .

This research highlighted the importance of behaviors - coffee consumption and not smoking in particular - on reduced mortality risk .

First author Maria Patrizia Carrieri from Aix Marseille University, Marseilles, France, observed that coffee consumption provides more protective effects on mortality in the HIV-HCV population than in the general population .

The research appears in the Journal of Hepatology . (ANI)

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