Racial differences in link between depression, early death in kidney disease sufferers

ANI | Updated: Nov 05, 2017 09:53 IST

Racial differences in link between depression, early death in kidney disease sufferers .

Washington D C  [USA], Nov 5 (ANI): Treatment of depressive symptoms may help lower the risk of early death in chronic kidney disease patients, but according to a recent study, racial differences may exist .

Depression is common, under-recognized, and undertreated among patients with chronic kidney disease, especially among racial/ethnic minorities .

Delphine Tuot from the University of California, San Francisco and her colleagues assessed the presence of depressive symptoms among 3725 participants in the Chronic Renal Insufficient Cohort (CRIC) .

The team found that 23 .3% of participants had depressive symptoms at the start of the study, with 17 .0% prevalence of anti-depressant use . The rate of death was 3 .37 per 100 person-years during a median of 6 .7 years of follow-up . (A person-year is the number of years of follow-up multiplied by the number of people in the study .)

In white individuals, those who experienced depressive symptoms had a 1 .5-fold higher risk of death than those without depressive symptoms, even when taking into consideration socioeconomic factors, severity of kidney disease, and burden of other chronic conditions .

This risk was much lower when the researchers accounted for use of anti-depressants, however . In black individuals, the presence of depressive symptoms was not linked to risk of death .

The findings suggested that depressive symptoms may be differentially associated with the risk of early death among white and black individuals with CKD .

Tuot noted that the study confirms prior research that depressive symptoms are common among individuals with CKD and suggests that there are potential long-term mortality benefits of treating depression among patients with mild to moderate kidney disease . More research is needed to understand differences in mortality risk among racial/ethnic subgroups .

The findings are presented at ASN Kidney Week 2017 at the Ernest N . Morial Convention Center in New Orleans, LA . (ANI)