At least 22 people died and more than 30 were seriously injured on Friday in a stampede at Mumbai's Elphinstone railway station.
Later, he told ANI, "I have ordered a high level enquiry headed by the Chief Safety Officer of Western Railways. The team will inquire about the matter and ascertain the cause of the incident."
The Railway Minister also expressed grief over the tragic incident and sympathized with the families of the deceased.
"I have just landed in Mumbai. It was an unfortunate incident. I am deeply grieved at tragic loss of innocent lives due to unfortunate stampede. I also wish for the early recovery of the injured people," he added.
"Such incident, in my Mumbai, is a matter of concern for me. We will remain committed to ensure that such incidents won't repeat in future," he added.
Meanwhile, Fadnavis also announced Rs. 5 lakh for the next of the kin of deceased and all the medical expenses of the injured will be borne by Government of Maharashtra.
"Saddened and shocked to know about the tragic stampede at #Elphinstone railway station, foot over bridge (sic)," Fadnavis wrote on Twitter.
Following the incident, the National Disaster Response Force (NDRF) team reached the site for rescue operation. (ANI)