Washington [US], December 23 (ANI): A research has found that people with inflammatory bowel disease (IBD) have more microplastics in their faeces than healthy controls, suggesting that the fragments could be related to the disease process.
The study has been published in the 'Environmental Science & Technology Journal'.
The prevalence of IBD, which includes Crohn's disease and ulcerative colitis, is rising globally. Characterized by chronic inflammation of the digestive tract, IBD can be triggered or made worse by diet and environmental factors.
Microplastics can cause intestinal inflammation, gut microbiome disturbances and other problems in animal models, so Faming Zhang, Yan Zhang and colleagues wondered if they could also contribute to IBD. As a first step toward finding out, the researchers wanted to compare the levels of microplastics in faeces from healthy subjects and people with different severities of IBD.
The team obtained faecal samples from 50 healthy people and 52 people with IBD from different geographic regions of China. Analysis of the samples showed that faeces from IBD patients contained about 1.5 times more microplastic particles per gram than those from healthy subjects. The microplastics had similar shapes (mostly sheets and fibres) in the two groups, but the IBD faeces had smaller (less than 50m) particles.
The two most common types of plastic in both groups were polyethylene terephthalate (PET; used in bottles and food containers) and polyamide (PA; found in food packaging and textiles).
People with more severe IBD symptoms tended to have higher levels of faecal microplastics. Through a questionnaire, the researchers found that people in both groups who drank bottled water ate takeaway food and were often exposed to dust had more microplastics in their faeces.
These results suggested that people with IBD may be exposed to more microplastics in their gastrointestinal tract. However, it's still unclear whether this exposure caused or contributed to IBD, or whether people with IBD accumulated more faecal microplastics as a result of their disease, the researcher said. (ANI)