Odisha got the first goal scoring chance of the match in the fourth minute when skipper Arjun Nayak attempted a header from Karthikach Bhola's corner. Unfortunately, the ball struck the crossbar and came back.
The deadlock finally broke in the 37th minute when Zomuanpuia headed the ball into the net from Lalrinpuia's cross from the left.
Lalsangzuala's men started the second half with greater intensity and looked hungry for more goals.
Their lead further increased in the 73rd minute when Odisha's goalkeeper Ejazuddin Khan came out of his line. Malsawmdawngliana kept his composure and pushed the ball into an empty net.
Mizoram hit the final nail in the 91st minute, thanks to a strike from F. Lalrinpuia.
They will next face Punjab on March 24 at Howrah Stadium, while Odisha will meet Karnataka on the same day at the Rabindra Sarobar Stadium. (ANI)