According to The Himalayan Times, rescue operations have begun and passengers were being taken out from the burning plane.
Emergency respondents and ambulances were seen rushing to the site of the incident.
Many airline jets en route to Kathmandu are turning back, including jets from Oman Air, Qatar Airways and FlyDubai.
The Tribhuvan International Airport has been closed to all departures and arrivals.
More details are awaited. (ANI)