The announcement greatly moves up the new embassy's initially scheduled opening in 2019, after US Secretary of State Rex Tillerson ended weeks of delays by approving a security plan, The Hill reported.
"The opening will coincide with Israel's 70th anniversary. The Embassy will initially be located in the Arnona neighborhood, in a modern building that now houses consular operations of the U.S. Consulate General Jerusalem," State Department spokeswoman Heather Nauert said in a statement.
"We are excited about taking this historic step, and look forward with anticipation to the May opening," the White House said in a statement.
Trump, who touted the Jerusalem move during a Friday speech, is also considering the possibility of accepting donations from wealthy Jewish-American donors to fund the permanent facility.
Jerusalem is considered a sacred place, which is home to Jewish, Christian and Muslim holy sites. However, it is also a disputed territory, contested by both Israel and Palestine, which sees it as a capital of its future state. (ANI)